Cell-Cell Interaction Mechanisms in Acute Lung Injury.

Shock
Huiting ZhouJie Fan

Abstract

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are caused by an exaggerated inflammatory response arising from a wide variety of pulmonary and systemic insults. Lung tissue is composed of a variety of cell populations, including parenchymal and immune cells. Emerging evidence has revealed that multiple cell populations in the lung work in concert to regulate lung inflammation in response to both direct and indirect stimulations. To date, the question of how different types of pulmonary cells communicate with each other and subsequently regulate or modulate inflammatory cascades remains to be fully addressed. In this review, we provide an overview of current advancements in understanding the role of cell-cell interaction in the development of ALI and depict molecular mechanisms by which cell-cell interactions regulate lung inflammation, focusing on inter-cellular activities and signaling pathways that point to possible therapeutic opportunities for ALI/ARDS.

References

Apr 1, 1990·Physiological Reviews·J S Pober, R S Cotran
Aug 12, 1967·Lancet·D G AshbaughB E Levine
Sep 1, 1983·The Journal of Trauma·E FaistG Heberer
May 1, 1983·Annals of Internal Medicine·A A FowlerT M Hyers
Jul 1, 1994·American Journal of Respiratory and Critical Care Medicine·K P SteinbergL D Hudson
Feb 1, 1997·The Journal of Clinical Investigation·N A DoyleC M Doerschuk
Apr 29, 1998·Nature·M Baggiolini
Jan 5, 2000·American Journal of Respiratory and Critical Care Medicine·W M KueblerA E Goetz
Apr 4, 2000·American Journal of Respiratory Cell and Molecular Biology·J FanO D Rotstein
May 4, 2000·The New England Journal of Medicine·L B Ware, M A Matthay
Jun 9, 2000·Annual Review of Physiology·T O Daniel, D Abrahamson
Nov 15, 2000·American Journal of Physiology. Lung Cellular and Molecular Physiology·E AbrahamJ Arcaroli
May 8, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Jie FanOri D Rotstein
Dec 25, 2002·Microscopy Research and Technique·Erika IivanainenKlaus Elenius
Apr 12, 2003·Critical Care Medicine·Edward Abraham
Jun 10, 2003·Critical Care Medicine·Christopher H GossUNKNOWN ARDS Network
Oct 17, 2003·The Journal of Clinical Investigation·Jie FanAsrar B Malik
Oct 18, 2003·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Derek W GilroyToby Lawrence
Jan 28, 2004·Cell·Juan S Bonifacino, Benjamin S Glick
Feb 26, 2004·The European Respiratory Journal·R Bals, P S Hiemstra
Mar 6, 2004·Science·Volker BrinkmannArturo Zychlinsky
Jun 24, 2004·Proceedings of the National Academy of Sciences of the United States of America·Benoit FevrierGraça Raposo
Mar 1, 2005·Journal of Leukocyte Biology·Huan YangKevin J Tracey
Apr 2, 2005·Nature Reviews. Immunology·Michael T Lotze, Kevin J Tracey
Sep 21, 2005·American Journal of Respiratory Cell and Molecular Biology·Michael A Matthay, Guy A Zimmerman
Nov 8, 2005·American Journal of Physiology. Lung Cellular and Molecular Physiology·Jie FanMark A Wilson
Dec 3, 2005·Proceedings of the American Thoracic Society·Thomas R Martin, Charles W Frevert
Jan 21, 2006·Respirology : Official Journal of the Asian Pacific Society of Respirology·Robert J Mason
May 8, 2007·Lancet·Arthur P Wheeler, Gordon R Bernard
May 15, 2007·American Journal of Physiology. Lung Cellular and Molecular Physiology·Alexandra V AndreevaTatyana A Voyno-Yasenetskaya
Nov 6, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Deepak A RaoJordan S Pober
Nov 4, 2008·American Journal of Respiratory Cell and Molecular Biology·Rachel L ZemansGregory P Downey
Mar 28, 2009·Critical Care Medicine·Sara E EricksonUNKNOWN NIH NHLBI ARDS Network
Apr 30, 2009·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Simon B RasmussenSøren R Paludan
May 13, 2009·The International Journal of Biochemistry & Cell Biology·Harriet CorvolLoic Guillot
May 15, 2009·Scandinavian Journal of Immunology·A CastellheimT E Mollnes
Aug 25, 2009·Trends in Immunology·Venizelos Papayannopoulos, Arturo Zychlinsky
Dec 8, 2009·Nature Cell Biology·Matias OstrowskiClotilde Thery
Mar 24, 2010·Critical Care Medicine·Bradford D WintersJonathan E Sevransky

❮ Previous
Next ❯

Citations

Jan 13, 2021·Shock·Linda E Sousse, Teresa A Zimmers

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.