Abstract
Bacillus subtilis is the best described member of the Gram positive bacteria. It is a typical rod shaped bacterium and grows by elongation in its long axis, before dividing at mid cell to generate two similar daughter cells. B. subtilis is a particularly interesting model for cell cycle studies because it also carries out a modified, asymmetrical division during endospore formation, which can be simply induced by starvation. Cell growth occurs strictly by elongation of the rod, which maintains a constant diameter at all growth rates. This process involves expansion of the cell wall, requiring intercalation of new peptidoglycan and teichoic acid material, as well as controlled hydrolysis of existing wall material. Actin-like MreB proteins are the key spatial regulators that orchestrate the plethora of enzymes needed for cell elongation, many of which are thought to assemble into functional complexes called elongasomes. Cell division requires a switch in the orientation of cell wall synthesis and is organised by a tubulin-like protein FtsZ. FtsZ forms a ring-like structure at the site of impending division, which is specified by a range of mainly negative regulators. There it recruits a set of dedicated division proteins to form ...Continue Reading
Citations
Mar 12, 2019·Future Microbiology·Imrich BarákNaďa Labajová
Apr 20, 2019·Molecular Microbiology·Beer Chakra SenKlas Flärdh
Feb 7, 2018·Frontiers in Microbiology·Katarína MuchováImrich Barák
Aug 14, 2019·Journal of Bacteriology·Lauren R HammondPrahathees J Eswara
Jul 15, 2020·Annual Review of Microbiology·Kanika KhannaKit Pogliano
Aug 9, 2020·Canadian Journal of Microbiology·Kusum SharmaJo-Anne R Dillon
Jul 24, 2020·MSphere·Robert S BrzozowskiPrahathees J Eswara
May 20, 2020·Nature Reviews. Microbiology·Alexander J F EganWaldemar Vollmer
Aug 20, 2020·Nature Communications·Ling Juan WuJeff Errington
Oct 1, 2020·Scientific Reports·Elodie FoulquierAnne Galinier
Dec 19, 2019·MBio·John T SaulsSuckjoon Jun
Aug 8, 2019·MBio·Jeanine RismondoAngelika Gründling
Dec 2, 2020·Antibiotics·Gabriele TrespidiSilvia Buroni
Feb 20, 2021·Applied Microbiology and Biotechnology·Zeli TangYan Huang
Apr 15, 2021·MBio·Helge FeddersenMarc Bramkamp
Oct 21, 2020·Journal of Bacteriology·Amit BhambhaniDaniel P Haeusser
Jun 10, 2021·Nature Communications·Phillip NußbaumSonja-Verena Albers
Jul 13, 2021·Frontiers in Microbiology·Anne GalinierFrédérique Pompeo
Jul 23, 2021·Cell Chemical Biology·Puneet LabanaChristopher N Boddy
Jul 14, 2021·MBio·Wei-Yue XingCheng-Cai Zhang
Jul 21, 2021·MBio·Jingqi ChenOscar P Kuipers
Aug 10, 2021·Frontiers in Cellular and Infection Microbiology·Ann L PowerJohn Love
Aug 20, 2021·Molecular Microbiology·Jordan DelisleThierry Doan