Cell cycle phase-specific death response of tobacco BY-2 cell line to cadmium treatment

Plant, Cell & Environment
Andrea KuthanovaZdenek Opatrny

Abstract

The character of programmed cell death (PCD) in plants differs in connection with the context, triggering factors and differentiation state of the target cells. To study the interconnections between cell cycle progression and cell death induction, we treated synchronized tobacco BY-2 cells with cadmium ions that represent a general abiotic stressor influencing both dividing and differentiated cells in planta. Cadmium induced massive cell death after application in all stages of the cell cycle; however, both the progression and the forms of the cell death differed pronouncedly. Apoptosis-like PCD induced by cadmium application in the S and G2 was characterized by pronounced internucleosomal DNA fragmentation. In contrast, application of cadmium in M and G1 phases was not accompanied by DNA cleavage, indicating suppression of autolysis and non-programmed character of the death. We interpret these results in the context of the situation in planta, where the induction of apoptosis-like PCD in the S and G2 phase might be connected with a need to preserve genetic integrity of dividing meristematic cells, whereas suppression of PCD response in differentiated cells (situated in G1/G0 phase) might help to avoid death of the whole plant,...Continue Reading

References

Feb 7, 1997·Cell·A G PaulovichL H Hartwell
Apr 6, 1999·Plant & Cell Physiology·T SanoT Nagata
Jan 12, 2001·Plant Physiology·A M Jones
Feb 24, 2001·Plant Molecular Biology·A FathR Jones
Jun 9, 2001·Methods in Cell Biology·A M JonesH Thomas
Aug 2, 2001·Journal of Experimental Botany·R J HerbertD Francis
Oct 18, 2001·Journal of Experimental Botany·L M SandalioL A del Río
Apr 9, 2002·Current Biology : CB·F F Severin, A A Hyman
Oct 1, 1996·The Plant Cell·J. L. DanglM. H. Richberg
Dec 21, 2002·Journal of Experimental Botany·Enrique OlmosEladio Hellín
Jul 31, 2004·Plant Physiology and Biochemistry : PPB·Andrea KuthanováMilena Cvikrová
Sep 14, 2004·The Plant Journal : for Cell and Molecular Biology·Yasuhiro KadotaKazuyuki Kuchitsu
Oct 15, 2005·Ecotoxicology and Environmental Safety·Tomás GichnerKaterina Demnerová
Jan 19, 2006·Archives of Environmental Contamination and Toxicology·E Skórzyńska-Polit, Z Krupa
Nov 10, 2006·The Plant Journal : for Cell and Molecular Biology·Maria Concetta de PintoLaura De Gara
Feb 8, 2008·Journal of Experimental Botany·Theresa J ReapePaul F McCabe
Apr 26, 2008·Journal of Experimental Botany·Andrea KuthanovaLukas Fischer

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Citations

Dec 11, 2008·Protoplasma·Ladislav TamásIgor Mistrík
May 26, 2012·Chemical Research in Toxicology·Cristina MonteiroMaria Celeste Dias
Jul 24, 2012·Plant Physiology and Biochemistry : PPB·Magdalena Arasimowicz-JelonekEdward A Gwóźdź
Feb 24, 2016·Journal of Integrative Plant Biology·Linda BrochhausenPeter Nick
Feb 28, 2018·Scientific Reports·Xiaolu XuPeter Nick
Aug 22, 2020·Journal of Experimental Botany·Jonas BertelsGerrit T S Beemster
Aug 25, 2019·International Journal of Molecular Sciences·Michiel HuybrechtsSophie Hendrix

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Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis