Cell death shapes embryonic lineages of the central complex in the grasshopper Schistocerca gregaria

Journal of Morphology
George S BoyanLeslie Williams

Abstract

We have investigated cell death in identified lineages of the central complex in the embryonic brain of the grasshopper Schistocerca gregaria. Progeny from these lineages lie in the pars intercerebralis and direct projections to the protocerebral bridge and then the central body via the w, x, y, z tracts. Osmium-ethyl gallate staining reveals pycnotic cells exclusively in cortical regions, and concentrated specifically within the lineages of the W, X, Y, Z neuroblasts. Minimal cell death occurs in a sporadic, nonpatterned manner, in other protocerebral regions. Immunohistochemistry reveals pycnotic cells express the enzyme cleaved Caspase-3 in their cytoplasm and are therefore undergoing programmed cell death (apoptosis). The number of pycnotic bodies in lineages of the pars intercerebralis varies with age: small numbers are present in the Y, Z lineages early in embryogenesis (42%), the number peaks at 67-80%, and then declines and disappears late in embryogenesis. Cell death may encompass up to 20% of a lineage at mid-embryogenesis. Peak cell death occurs shortly after maximum neurogenesis in the Y, Z lineages, and is maintained after neurogenesis has ceased in these lineages. Cell death within a lineage is patterned. Apoptosi...Continue Reading

References

Aug 10, 1976·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J G WhiteS Brenner
Nov 1, 1992·Journal of Neurobiology·J W TrumanS Robinow
Jan 1, 1992·Experimental Gerontology·J W Truman
Mar 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·C S GoodmanN C Spitzer
Jan 1, 1984·Annual Review of Neuroscience·J W Truman
Jun 1, 1983·The Journal of Comparative Neurology·J W Truman
Jan 1, 1982·Neuroscience·K Herrup, S L Wilczynski
Apr 29, 1994·Science·K WhiteH Steller
Oct 1, 1995·Progress in Neurobiology·I Naruse, H Keino
Jun 25, 1999·Cell Death and Differentiation·C Kitanaka, Y Kuchino
Jan 26, 2002·Microscopy Research and Technique·Uwe Homberg
Oct 3, 2002·Nature Reviews. Molecular Cell Biology·Eric H Baehrecke
Dec 3, 2003·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·M Mappes, U Homberg
Feb 1, 1995·Trends in Cell Biology·K White, H Steller
Apr 21, 2004·European Journal of Biochemistry·Cinthya Assunção Guimarães, Rafael Linden
Jul 18, 2006·Annual Review of Cell and Developmental Biology·Bruce A Hay, Ming Guo
Sep 22, 2006·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Martina Mappes, Uwe Homberg
Nov 4, 2006·Cell Death and Differentiation·S Kumar
Dec 14, 2006·Development·Ana Rogulja-OrtmannGerhard M Technau
Sep 28, 2007·Current Molecular Medicine·François Paquet-Durand, Gerd Bicker
Jul 8, 2008·Methods in Enzymology·Donna DentonSharad Kumar
Oct 11, 2008·Cell Death and Differentiation·G KroemerUNKNOWN Nomenclature Committee on Cell Death 2009
Sep 19, 2009·Development·Abhilasha KumarHeinrich Reichert
Nov 1, 1997·Development Genes and Evolution·G S Boyan, J L D Williams

❮ Previous
Next ❯

Citations

Mar 9, 2011·Arthropod Structure & Development·George Boyan, Leslie Williams
Apr 9, 2016·Development Genes and Evolution·Nikolaus Dieter Bernhard KoniszewskiGregor Bucher

❮ Previous
Next ❯

Related Concepts

Related Feeds

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis