Cell Division Modes and Cleavage Planes of Neural Progenitors during Mammalian Cortical Development

Cold Spring Harbor Perspectives in Biology
Fumio Matsuzaki, Atsunori Shitamukai

Abstract

During mammalian brain development, neural progenitor cells undergo symmetric proliferative divisions followed by asymmetric neurogenic divisions. The division mode of these self-renewing progenitors, together with the cell fate of their progeny, plays critical roles in determining the number of neurons and, ultimately, the size of the adult brain. In the past decade, remarkable progress has been made toward identifying various types of neuronal progenitors. Recent technological advances in live imaging and genetic manipulation have enabled us to link dynamic cell biological events to the molecular mechanisms that control the asymmetric divisions of self-renewing progenitors and have provided a fresh perspective on the modes of division of these progenitors. In addition, comparison of progenitor repertoires between species has provided insight into the expansion and the development of the complexity of the brain during mammalian evolution.

Citations

Dec 23, 2015·Development, Growth & Differentiation·Tetsuo Yasugi, Takashi Nishimura
Jun 4, 2016·Current Opinion in Neurobiology·Michaela Wilsch-BräuningerWieland B Huttner
Sep 15, 2016·Frontiers in Cell and Developmental Biology·Philipp Kaldis
Mar 24, 2018·Journal of Neurochemistry·Ana UzquianoFiona Francis
Jun 8, 2019·Journal of Anatomy·Stephan C CollinsFiona Francis
Mar 31, 2018·Frontiers in Neuroscience·Ugo BorelloColette Dehay
Aug 31, 2019·EMBO Reports·Gabriella ShullElena Taverna
Sep 5, 2019·Frontiers in Cellular Neuroscience·Maxime PenissonFiona Francis
Mar 28, 2019·Frontiers in Cell and Developmental Biology·Argyro KalogeropoulouStavros Taraviras
Aug 1, 2020·Frontiers in Cell and Developmental Biology·Lisa M Julian, William L Stanford
Aug 31, 2020·Cerebral Cortex Communications·Runxiang QiuQiang Lu
Oct 2, 2020·Physiological Reviews·Rico SchieweckMichael A Kiebler
Jun 5, 2021·Seminars in Cell & Developmental Biology·Belal ShohayebHelen M Cooper
Jun 24, 2021·Nature Reviews. Molecular Cell Biology·Terry Lechler, Marina Mapelli
May 18, 2021·The EMBO Journal·Martim Dias Gomes, Sandra Iden

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adult Stem Cells

Adult stem cells reside in unique niches that provide vital cues for their survival, self-renewal, and differentiation. They hold great promise for use in tissue repair and regeneration as a novel therapeutic strategies. Here is the latest research.

Related Papers

Development, Growth & Differentiation
Atsunori Shitamukai, Fumio Matsuzaki
Current Opinion in Neurobiology
Weimin Zhong, William Chia
Development, Growth & Differentiation
Yoichi Kosodo, Wieland B Huttner
© 2021 Meta ULC. All rights reserved