Cell fate decisions and patterning in the vertebrate retina: the importance of timing, asymmetry, polarity and waves

Current Opinion in Neurobiology
Jarema Malicki

Abstract

The differentiation of distinct cell populations in the retina is a multi-step process that involves cell cycle exit, migration, and dramatic changes of cell morphology. All these steps are tightly controlled by multiple regulatory pathways, which involve both cell-autonomous networks of transcription factors and cell-cell signaling events. Additional regulatory inputs into cell fate decisions have been recently suggested: accumulating evidence shows that the timing of cell cycle exit, the orientation of the mitotic spindle during the last cell division, and the polarity of neuronal progenitor cells could play important roles in cell fate determination.

References

May 9, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Devid DamianiEnrica Strettoi
Jan 24, 2007·Proceedings of the National Academy of Sciences of the United States of America·Edwin C T OhAnand Swaroop
Apr 17, 2010·Biochemical and Biophysical Research Communications·Shao-Yun Jiang, Jian-Tao Wang
Jul 8, 2008·Gene Expression Patterns : GEP·May Shawi, Fabrizio C Serluca
Apr 15, 2008·Experimental Eye Research·Ilse GosensRonald Roepman
Jun 15, 2007·Brain Research·Lisa M Baye, Brian A Link
Aug 20, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Ruben Adler
Nov 28, 2008·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Satish S Kitambi, Jarema Malicki
Jan 19, 2008·Proteomics·Marie-Laure BaudetSteve Harvey
Jan 17, 2012·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Sherry G ClendenonJames A Marrs
Apr 1, 2011·The Journal of Comparative Neurology·N ZabouriC Casanova
Jan 29, 2010·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Aikaterini Bilitou, Shin-ichi Ohnuma
May 27, 2010·Developmental Dynamics : an Official Publication of the American Association of Anatomists·N E RawsonA-S LaMantia
Oct 3, 2006·Experimental Eye Research·Carolyn O'DriscollThomas G Cotter
Apr 7, 2010·Mechanisms of Development·Masahiro YamaguchiIchiro Masai
Aug 26, 2014·Mechanisms of Development·Rebecca SinnJoachim Wittbrodt
Oct 13, 2009·Current Opinion in Genetics & Development·Juan Ramon Martinez-Morales, Joachim Wittbrodt
Apr 11, 2006·Developmental Biology·Zac PujicJarema Malicki
Aug 27, 2005·Developmental Biology·Rebecca L BradfordRuben Adler
Jul 29, 2006·Developmental Biology·Ernesto F Moreira, Ruben Adler
Mar 19, 2014·Journal of Theoretical Biology·Sang-Woo LeeYoshihiro Morishita
Jul 5, 2011·Polish Journal of Veterinary Sciences·D ChrobakM Binek
Jul 22, 2010·Nature Reviews. Neuroscience·Anand SwaroopDouglas Forrest
Aug 4, 2006·Human Molecular Genetics·Agnes G S H van RossumJan Wijnholds
Dec 21, 2005·The Journal of Cell Biology·Lucia PoggiWilliam A Harris
Mar 30, 2020·Scientific Reports·G B CollinP M Nishina

Citations

Sep 4, 1995·The Journal of Comparative Neurology·Pamela A RaymondG A Curran
Sep 7, 2000·The Journal of Comparative Neurology·M Xiao, A Hendrickson
Sep 14, 2000·Neuron·Ichiro MasaiStephen W Wilson
Sep 23, 2000·Science·C J Neumann, C Nuesslein-Volhard
Jan 13, 2001·Genes & Development·S W WangL Gan
Feb 15, 2001·Proceedings of the National Academy of Sciences of the United States of America·W LiuM Xiang
Oct 10, 2001·Current Biology : CB·S Horne-BadovinacS Abdelilah-Seyfried
Nov 2, 2002·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Deborah L StenkampEmily E Shupe
Jun 12, 2003·Developmental Biology·Deborah L Stenkamp, Ruth A Frey

Related Concepts

Vertebrates
Photoreceptors
Embryo
Biochemical Pathway
Cortex Bone Disorders
Cell Fate
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Ganglion Cell
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