Cell fusion in Neurospora crassa

Current Opinion in Microbiology
Stephanie HerzogAndré Fleissner

Abstract

In recent years, the filamentous fungus Neurospora crassa has advanced as a model organism for studying eukaryotic cell-cell communication and fusion. Cell merger in this fungus employs an unusual mode of communication, in which the fusion partners appear to switch between signal sending and receiving. Many molecular factors mediating this intriguing mechanism and the subsequent membrane merger have been identified. It has become apparent that conserved factors, such as MAP kinases, NADPH oxidases and the STRIPAK complex, together with fungal specific proteins are wired into an intricate signaling network. Here, we will present an overview of recent findings on the molecular mechanism mediating fusion in N. crassa and will discuss the current working model.

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Citations

Apr 2, 2016·Seminars in Cell & Developmental Biology·André Fleißner, Stephanie Herzog
Apr 4, 2016·Seminars in Cell & Developmental Biology·Robert Marschall, Paul Tudzynski
Jun 9, 2016·Current Biology : CB·Andrew B Goryachev, Marcin Leda
Jul 31, 2016·Seminars in Cell & Developmental Biology·Daisuke MaruyamaTetsuya Higashiyama
Dec 23, 2016·Proceedings. Biological Sciences·David Vogel, Audrey Dussutour
Apr 18, 2020·Biological Reviews of the Cambridge Philosophical Society·Miguel A Naranjo-Ortiz, Toni Gabaldón
Oct 30, 2016·Proceedings of the National Academy of Sciences of the United States of America·Martin WeichertAndré Fleißner
Jan 15, 2020·Applied Microbiology and Biotechnology·Leandro Lopes da SilvaMarisa Vieira de Queiroz
Apr 20, 2019·Frontiers in Microbiology·Monika S Fischer, N Louise Glass
Dec 10, 2020·Computational and Structural Biotechnology Journal·Zhanquan ZhangShiping Tian
Oct 15, 2020·Cells·Alexander P MelaN Louise Glass
Dec 13, 2017·Fungal Genetics and Biology : FG & B·Norio Takeshita
Mar 4, 2017·Microbiology Spectrum·Asen DaskalovN Louise Glass
May 20, 2017·Microbiology Spectrum·Mark D FrickerLynne Boddy

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