Cell-mediated immune responses in malnourished host

Journal of Tropical Pediatrics
S FakhirA Rattan

Abstract

One hundred children in the age group 6 months to 5 years were investigated for cell-mediated immune response in relation to their nutrition. The nutritional status was assessed by the Wellcome classification. The majority (54 per cent) of children had marasmus. Absolute lymphocyte count was found to be significantly low (P less than 0.01) in all malnourished groups except in mild forms of undernutrition. Small lymphocytes were also found to be significantly decreased (P less than 0.001) in malnourished children. A significant depression (P less than 0.001) was observed in the percentage and absolute T cells in all the malnourished children with kwashiorkor who showed the maximum depression of counts. All the control children showed DNCB skin reactions above grade 2+ while only 39 per cent of malnourished children showed reaction of this grade. After 4-6 weeks of dietary therapy, T cell counts were comparable with control values and DNCB skin test returned to normal in more than 75 per cent of cases.

Citations

Aug 26, 2014·PloS One·Maren Johanne Heilskov RytterVibeke Brix Christensen
Dec 29, 2010·Journal of Medicinal Food·Mamdouh Abdulmaksoud AbdulrhmanMarwa Wageh Abu El Naga
Jan 30, 2007·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Ray Y ChenMichael S Saag
Apr 1, 1996·The Pediatric Infectious Disease Journal·R P ReedM Khoosal
Apr 20, 2002·Journal of Pediatric Gastroenterology and Nutrition·Edgar Vásquez-GaribayBarbara Vizmanos-Lamotte

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Related Papers

Journal of the European Academy of Dermatology and Venereology : JEADV
S HeilskovM S Deleuran
Journal of Pediatric Gastroenterology and Nutrition
F O AkenamiA Vaheri
© 2022 Meta ULC. All rights reserved