Cell-mediated immune responses in sporotrichosis

The Journal of Infectious Diseases
J F PlouffeR Browne

Abstract

Cell-mediated immunity (CMI) was evaluated in five patients with cutaneous sporotrichosis and six patients with systemic sporotrichosis. Whereas patients with cutaneous disease showed normal CMI, the patients with systemic disease had significant abnormalities in CMI. Most patients exhibited responses to a sporothrix antigen, measured either in conventional assays of lymphocyte transformation or in preincubation assays. Two patients with protracted illnesses and continued abnormalities in CMI were treated with transfer factor and showed improvement in parameters of CMI and control of their disease.

Citations

Jan 1, 1979·Journal of Immunological Methods·J F Plouffe
Oct 1, 1985·Veterinary Immunology and Immunopathology·P F Lehmann
Apr 1, 1984·Diagnostic Microbiology and Infectious Disease·M A MorganG D Roberts
Dec 12, 2001·International Journal of Dermatology·A GordhanJ Aboobaker
Oct 1, 1994·International Journal of Dermatology·A H Werner, B E Werner
Nov 21, 2013·Revista iberoamericana de micología·José A Martínez-ÁlvarezHéctor M Mora-Montes
Nov 1, 1983·International Journal of Dermatology·L C Sperling, S I Read
Apr 1, 1983·International Journal of Dermatology·S J Friedman, J A Doyle
Aug 1, 1995·The Australasian Journal of Dermatology·M J Whitfeld, H B Faust
Jun 1, 1982·Australian Veterinary Journal·R I Miller, R S Campbell
Jun 1, 1988·Journal of the American Geriatrics Society·C A Kauffman, M S Terpenning
Jan 1, 1988·International Journal of Dermatology·J M SchamrothP Kellen
Jan 1, 1988·Scandinavian Journal of Infectious Diseases·A M VeljiR Slovak
Nov 25, 1983·Mycopathologia·C E Meléndez RuizR Ramos Zepeda
Jan 16, 2019·Journal of Fungi·Flavio Queiroz-TellesGil Benard
Aug 1, 1981·Infection and Immunity·R W Bradsher, R H Alford
Dec 1, 1980·Microbiological Reviews·L R Travassos, K O Lloyd
May 1, 1993·Journal of the American Academy of Dermatology·R S PurvisS K Tyring

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