PMID: 6976672Jun 1, 1981Paper

Cell-mediated immunity in acute idiopathic optic neuritis and multiple sclerosis

Acta Neurologica Scandinavica
H J Sagar, I D Allonby

Abstract

Lymphocyte transformation responses to phytohaemagglutinin, measles antigen and tuberculin and the absolute numbers of circulating T and SIg+ cells were determined in 16 patients with acute idiopathic optic neuritis (ON), 42 patients with multiple sclerosis (MS) and 78 healthy controls. Patients with acute ON showed impaired lymphocyte transformation responses in both autologous plasma and AB serum similar in extent to those seen in MS patients in relapse. They were not associated with a reduced total number of circulating T cells.

References

Jan 1, 1977·British Medical Bulletin·S C Knight
Nov 1, 1978·Acta Neurologica Scandinavica·H Nyland, A Naess
Sep 1, 1979·Journal of the Neurological Sciences·H J Sagar, I D Allonby
Sep 1, 1978·Brain : a Journal of Neurology·D A CompstonW I McDonald
Mar 1, 1976·Journal of Neurology, Neurosurgery, and Psychiatry·W M Hutchinson
Nov 1, 1970·The British Journal of Ophthalmology·S LessellM Kies
Jan 1, 1972·International Archives of Allergy and Applied Immunology·B Zweiman
Feb 1, 1981·Acta Neurologica Scandinavica·H J SagarP Hughes
Feb 20, 1964·The New England Journal of Medicine·S STARR, S BERKOVICH

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Citations

Aug 1, 1982·Australian and New Zealand Journal of Medicine·J G McLeod

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