Cell-mediated immunity in experimental Nocardia asteroides infection.

Infection and Immunity
T Sundararaj, S C Agarwal

Abstract

Experimental mycetoma-like lesions developed in guinea pigs after subcutaneous injection of Nocardia asteroides. Although delayed hypersensitivity appeared earlier, increased macrophage migration inhibition and microbicidal activity appeared after 7 weeks. When the lesions healed, high cell-mediated immunity was present. Cell-mediated immunity was transferred to normal recipient guinea pigs from healed donor guinea pigs by spleen cell transfer. Recipient guinea pigs showed marked protection against challenge with N. asteroides.

References

Oct 1, 1975·American Journal of Clinical Pathology·T K Ruebush, J S Goodman
Feb 1, 1973·Infection and Immunity·S K MishraS Abraham

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Citations

Dec 1, 1983·The Journal of Hygiene·B L Beaman, A M Sugar
Jun 1, 1981·Sabouraudia·V ChitravelS Kunjithapadam
Nov 1, 1996·World Journal of Microbiology & Biotechnology·O U Osoagbaka
Apr 1, 1994·Clinical Microbiology Reviews·B L Beaman, L Beaman
Aug 1, 1980·Infection and Immunity·B L BeamanY Ohsugi
Feb 1, 1980·Infection and Immunity·G A FiliceJ S Remington
Dec 1, 1982·Infection and Immunity·R L DeemM E Gershwin

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