PMID: 6987593Jan 1, 1980Paper

Cell-mediated immunity study by skin testing in 129 critically ill patients (author's transl)

G OffenstadtP Amstutz


Delayed hypersensitivity skin testing was performed in 129 critically ill patients. Six intradermal antigens were used: tuberculin, candidin, varidase, epidermophytin, trichophytin and CCB (a polyvalent microbial vaccine from the Pasteur Institute). The response was judged as positive when one test or more were positive. Patients were devided in four groups: group A (40 cases): non-infected patients, a priori without immunodeficiency; group B (14 cases); suspected of immunodeficiency (cancers, hemopathies, collagen diseases receiving corticosteroids); group C (24 cases): decompensated chronic respiratory insufficienceis; group D (50 cases): overwhelming sepsis (septicaemias, septic acute respiratory distress syndromes, thoracic empyemas, purulent meningitis, peritonitis, mediastinitis). A significant diminution of delayed hypersensitivity was observed in groups B, C and D. No relation was found between delayed hypertensitivity and prognosis in groups C and D.

Related Concepts

Care of Intensive Care Unit Patient
Delayed Hypersensitivity
Cellular Immune Response
Immune System Diseases
Prausnitz-Kustner Test
Hypersensitivity Skin Testing
Tuberculin Test

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