Cell membranes: A subjective perspective

Biochimica Et Biophysica Acta
Kai Simons

Abstract

Cell membranes have developed a tremendous complexity of lipids and proteins geared to perform the functions cells require. The lipids have for long remained in the background and are now regaining their role as important building blocks of cells. Their main function is to form the matrix of our cell membranes where they support a variety of functions essential for life. This 2-dimensional fluid matrix has evolved unexpected material properties that involve both lipid-lipid and lipid-protein interactions. This perspective is a short summary of the challenges that this field faces and discusses potential ways and means for coming to grips with the properties of this incredible fluid. This article is part of a Special Issue entitled: Biosimulations edited by Ilpo Vattulainen and Tomasz Róg.

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Citations

Jun 19, 2016·Biochimica Et Biophysica Acta·Ilpo Vattulainen, Tomasz Róg
Mar 24, 2017·The Journal of Cell Biology·Masanao KinoshitaMichio Murata
Jan 26, 2017·Frontiers in Cell and Developmental Biology·Mary L Kraft
Dec 20, 2019·Biomedical Optics Express·Adrianna MilewskaKristjan Leosson
Mar 4, 2021·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Tamir Dingjan, Anthony H Futerman
Apr 26, 2018·Biophysical Journal·Thais A EnokiGerald W Feigenson
Jul 8, 2020·International Journal of Molecular Sciences·Jinsha Liu, Sepideh Afshar
Dec 7, 2019·Biochimica Et Biophysica Acta. Biomembranes·Sven C D van IJzendoornAma Gassama-Diagne

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