Cell proliferation in the ectoderm of the Xenopus embryo: development of substratum requirements for cytokinesis

Developmental Biology
R Winklbauer

Abstract

The requirements for cell division in ectodermal blastomeres of the early Xenopus embryo were studied. Isolated blastomeres divide autonomously on nonadhesive agar in a simple salt solution up to the midblastula stage. After the midblastula transition, cell-cell contact is required for blastomere division. In isolated blastomeres of that stage, cytokinesis fails, but nuclear division continues normally for some time. Cell-cell contact as a prerequisite for blastomere division can be replaced by culturing blastomeres on an appropriate substratum. Clonal growth of isolated blastomeres is supported by a variety of protein substrata, indicating rather unspecific substratum requirements. Different substrata which do not support blastomere division can affect different steps in cytokinesis.

References

Apr 1, 1979·The Journal of Cell Biology·K HedmanM Höök
May 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·J W Sanger
Jan 1, 1985·Journal of Cellular Biochemistry·K M YamadaW T Chen
Sep 1, 1972·The Journal of Cell Biology·T Elsdale, J Bard
Jun 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·T E Schroeder
Jan 1, 1984·Annual Review of Biochemistry·R James, R A Bradshaw
Jan 1, 1983·The Journal of Cell Biology·K S StennV P Terranova
Jul 1, 1984·Cell·J W Newport, M W Kirschner
Mar 1, 1980·Analytical Biochemistry·D Barnes, G Sato
Jan 1, 1980·Journal of Supramolecular Structure·R A Bradshaw, J S Rubin
Dec 1, 1980·Cell·D Barnes, G Sato
Sep 1, 1983·Wilhelm Roux's Archives of Developmental Biology·Elze C BoterenbroodKoki Hara

❮ Previous
Next ❯

Citations

Jan 1, 1997·Cell Motility and the Cytoskeleton·A Selchow, R Winklbauer
Dec 1, 1992·Developmental Dynamics : an Official Publication of the American Association of Anatomists·R WinklbauerB Angres
Dec 1, 1991·Developmental Biology·R Winklbauer, M Nagel
Jan 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·E BaltusJ Brachet
Feb 10, 2009·The Journal of Biological Chemistry·Ann Y J ParkJun-Lin Guan
Jun 10, 2005·Molecular Biology of the Cell·Masamitsu KanadaTaro Q P Uyeda
Nov 1, 2001·Annual Review of Cell and Developmental Biology·M Glotzer
Dec 14, 2007·Proceedings of the National Academy of Sciences of the United States of America·Minna ThullbergStaffan Strömblad
May 1, 1989·Differentiation; Research in Biological Diversity·D WedlichG Klein
Aug 16, 2005·Current Opinion in Cell Biology·Ray Keller
Aug 16, 2006·The Journal of Cell Biology·Carlos G ReverteSusan E LaFlamme
Jun 1, 1990·Roux's Archives of Developmental Biology : the Official Organ of the EDBO·Marc ServetnickPeter Hausen
May 1, 1988·Roux's Archives of Developmental Biology : the Official Organ of the EDBO·Rudolf Winklbauer
Nov 29, 2013·Journal of Cell Science·Shomita S MathewSusan E Laflamme

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.