PMID: 2503623Sep 1, 1989Paper

Cell surface expression of several species of human immunodeficiency virus type 1 major core protein

Journal of Virology
A LaurentA G Hovanessian

Abstract

The major core protein (p25) of the human immunodeficiency virus type 1 (HIV-1) was characterized by two-dimensional-gel isoelectric focusing. The p25 detectable in HIV-1-infected cells is composed of four species with related isoelectric points. This is due in part to the phosphorylated state of p25. The four species of p25 are expressed on the cell surfaces of infected cells, but only the two most basic species are incorporated into the HIV-1 virion. These findings emphasize the importance of p25 in understanding infection with HIV and might have implications for the development of vaccines.

References

Nov 1, 1985·Annals of Internal Medicine·M EssexT H Lee
Jul 23, 1987·Nature·B D WalkerR T Schooley
Nov 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·R O Hynes

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Citations

Aug 1, 1993·AIDS Research and Human Retroviruses·A G Laurent-CrawfordA G Hovanessian
Apr 18, 1998·AIDS Research and Human Retroviruses·S H PincusK S Wise
Jun 10, 2010·The Journal of Biological Chemistry·Shogo MisumiShozo Shoji
Jun 1, 1992·Journal of Medical Virology·L FrankeR von Baehr
Mar 30, 2001·Virology·C CallebautA G Hovanessian
Jul 31, 1998·Micron : the International Research and Review Journal for Microscopy·T GotoK Ikuta
Dec 1, 1991·Virology·A G Laurent-CrawfordA G Hovanessian

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