PMID: 6407157DOI: 10.1016/0035-9203(83)90037-8Jan 1, 1983Paper
Cell surface glycoproteins of Trypanosoma cruzi: protective immunity in mice and antibody levels in human chagasic sera
Transactions of the Royal Society of Tropical Medicine and Hygiene
D Snary
Abstract
Two cell surface glycoproteins from Trypanosoma cruzi have been compared for their ability to protect mice against an acute lethal infection. One of these, a 90,000 glycoprotein found on all stages of the parasite, protected against both bloodstream and metacyclic trypomastigote challenge. A 72,000 glycoprotein found only on insect-derived stages of T. cruzi protected only against a metacyclic trypomastigote challenge. Antibody against both of these glycoproteins was present in human chagasic sera.
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Jun 1, 1984·International Journal for Parasitology·A OsunaM C Mascaro
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