Abstract
Retrospective observational. To compare objective (neurological examination) and subjective (patients perception) recovery in patients with spinal cord injury (SCI) who chose to undergo cell transplantation therapies (CTT) outside of clinical trials abroad. Physical Medicine and Rehabilitation Hospital, Kuwait. Nine patients with SCI who had undergone CTT outside Kuwait were identified and their neurological pre-transplantation evaluation according the International Standards for Neurological Classification of SCI (ISNCSCI) was collected from hospital records. Post transplantation ISNCSCI examination was conducted during follow-up visits and scores were completed between pre and post CTT. In addition to the ISNCSCI evaluation, change in disability status, and patient's perception of improvement after stem cell transplantation were examined. Overall, 8 males and 1 female with chronic SCI underwent CTT (42 ± 38.2 months post SCI) in various centers (China, Egypt, Germany, India, and Iran). On follow-up post CTT assessment (89.2 ± 36 months post SCI), 55.5% of individuals reported perceived improvement as follows: increased deep tissue sensation below the injury (100%) or increase in bladder sensation (11.1%). Objective examinatio...Continue Reading
References
May 13, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Hans S KeirsteadOswald Steward
Jul 29, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Qilin CaoScott R Whittemore
Feb 10, 2006·Neurorehabilitation and Neural Repair·Bruce H DobkinJames Guest
Dec 21, 2006·Spinal Cord·D LammertseUNKNOWN International Campaign for Cures of Spinal Cord Injury Paralysis
Dec 21, 2006·Spinal Cord·J W FawcettD Short
Feb 15, 2007·PLoS Medicine·Jun YanVassilis E Koliatsos
May 7, 2009·Spinal Cord·A BlightJ D Guest
Feb 12, 2010·Journal of Neurotrauma·Wolfram TetzlaffBrian K Kwon
Aug 18, 2010·Spinal Cord·J D SteevesUNKNOWN EMSCI Study Group
Feb 15, 2012·The Journal of Spinal Cord Medicine·Steven C KirshblumWilliam Waring
Jun 5, 2013·Cytotherapy·Saeed Oraee YazdaniMasoud Soleimani
Aug 21, 2013·Brain Research·Guanghui DaiRuxiang Xu
Oct 25, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Shaoping HouArmin Blesch
Nov 20, 2014·Stem Cell Research & Therapy·Marcus Vinícius MendonçaRicardo Ribeiro Dos Santos
Jan 15, 2015·Journal of Neurotrauma·Jordan W SquairAndrei V Krassioukov
Feb 27, 2016·Neuroscience·M YousefifardM Hosseini
May 26, 2017·Neurosurgery·Allan D LeviRaphael Guzman