PMID: 12889352Aug 2, 2003

Cellular and humoral immunity in patients with acute disorder of coronary circulation

Likars'ka sprava
V D SyvolapV V Syvolap


The condition was studied of cell-bound and humoral immunity in patients with ischemic heart disease. The data secured permit reaching the conclusion that the unstable clinical course of angina pectoris is accompanied by unspecific alterations in the cellular link of immunity such as increase in the absolute number of T-lymphocytes and T-suppressors. In patients with myocardial infarction, in the acute period of the illness there develop inflammatory reactions involving participation of cell-bound (neutrophilic leucocytosis, a drop in the absolute number of acidophilic granulocytes, absolute number of lymphocytes, T-lymphocytes, T-suppressors, increase in T-helpers--T-suppressors ratio; decline in T-lymphocytes activity) and humoral (a drop in the level of Ig A, increase in blood serum concentration of circulating immune complexes) links of immunity.

Related Concepts

Acute Disease
Myocardial Preinfarction Syndrome
Antibody Formation
Coronary Circulation
Cellular Immune Response
Myocardial Infarction
Lymphocyte Count Measurement

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