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Cellular and molecular determinants of cisplatin resistance

European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)

Sep 1, 1998

Raymond P Perez

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Abstract

Cisplatin and carboplatin are among the most active and widely used cytotoxic anticancer drugs. However, the acquisition or presence of resistance significantly undermines the curative potential of these drugs against many malignancies. Multiple potential mechanisms of resistance have b...read more

Mentioned in this Paper

NSC-119875
Platinol
Antineoplastic Agents
DNA Damage
DNA, Neoplasm
Reflex, Abnormal
Genetic Translation Process
Biochemical Pathway
Mismatch Repair
Sulfhydryl Compounds
90
Paper Details
References
  • References61
  • Citations106
  • References61
  • Citations106
12345...

Cellular and molecular determinants of cisplatin resistance

European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)

Sep 1, 1998

Raymond P Perez

PMID: 9893624

DOI: 10.1016/s0959-8049(98)00227-5

Abstract

Cisplatin and carboplatin are among the most active and widely used cytotoxic anticancer drugs. However, the acquisition or presence of resistance significantly undermines the curative potential of these drugs against many malignancies. Multiple potential mechanisms of resistance have b...read more

Mentioned in this Paper

NSC-119875
Platinol
Antineoplastic Agents
DNA Damage
DNA, Neoplasm
90

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Paper Details
References
  • References61
  • Citations106
  • References61
  • Citations106
12345...

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