Cellular basis of the non-specific potentiation of the immunoglobulin E response after helminth parasite infection

Veterinary Parasitology
J F Urban

Abstract

Helminth parasites induce a substantial increase in the production of immunoglobulin E (IgE) by the host after infection. Only a portion of the IgE antibody produced is specific for parasite-derived antigens since production of IgE antibody to non-parasite-derived antigens is also stimulated after infection. Investigators have recently observed, in the parasite-infected host, the appearance of both T and B lymphocytes that synthesize lymphokines that affect the production of IgE in vitro. The results of some of these studies will be reviewed presently, and the possible role of lymphokines in the increase of IgE production after helminth infection will be discussed.

References

Jan 1, 1979·Scandinavian Journal of Immunology·U Hellström, H L Spiegelberg
Jan 1, 1969·International Archives of Allergy and Applied Immunology·R Revoltella, Z Ovary
May 3, 1972·Nature: New Biology·A Schimpl, E Wecker
Aug 2, 1974·Nature·E Jarrett, A Ferguson
Oct 1, 1972·Journal of Comparative Pathology·M E Barratt, I V Herbert

❮ Previous
Next ❯

Citations

May 1, 2012·The Journal of Allergy and Clinical Immunology·Helton C SantiagoThomas B Nutman
Jul 10, 2019·Current Protein & Peptide Science·Ju Yeong KimTai-Soon Yong
Nov 19, 2014·The Journal of Immunology : Official Journal of the American Association of Immunologists·Helton da Costa SantiagoThomas B Nutman

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antibody Specificity

Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.