Cellular colocalization of Fos and neuropeptide Y in the intergeniculate leaflet after nonphotic phase-shifting events

Brain Research
D JanikN Mrosovsky

Abstract

Nonphotic and photic stimuli that phase shift circadian rhythms were presented to hamsters, Mesocricetus auratus. The nonphotic stimulus was a 3-h pulse of novelty-induced wheel running starting at circadian time 4-5. The photic stimulus used was a 0.5 h light pulse starting at circadian time 18. Double immunocytochemistry was used to determine the neurochemical phenotype of cells in the intergeniculate leaflet that were activated by these stimuli. Both the nonphotic and the photic phase-shifting stimuli induced the expression of c-fos in the intergeniculate leaflet compared to unstimulated controls. However, after nonphotic stimulation, Fos-like immunoreactivity was common in neurons that also were NPY positive. Such colocalization of Fos and NPY after photic stimuli was rare. These findings suggest that the NPY pathway from the intergeniculate leaflet to the suprachiasmatic nucleus carries information about nonphotic events.

Citations

Aug 1, 1996·Biological Reviews of the Cambridge Philosophical Society·N Mrosovsky
Feb 19, 2008·The European Journal of Neuroscience·Ian C WebbRalph E Mistlberger
Aug 1, 1997·The European Journal of Neuroscience·E S MaywoodM H Hastings
Apr 27, 2004·Neuroreport·Gregory H GrossmanJ David Glass
Jul 5, 2003·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·R E MistlbergerM S Pollock
Apr 10, 2010·The European Journal of Neuroscience·J David GlassJessie M Francl
Apr 24, 2014·BioMed Research International·Morten MøllerCorin Badiu
Jun 12, 2014·Journal of Biological Rhythms·Jennifer LangelLaura Smale
Nov 16, 2007·The European Journal of Neuroscience·Carolina EscobarRuud M Buijs
Dec 6, 2005·The European Journal of Neuroscience·Jorge MendozaCarolina Escobar
Dec 13, 2006·The European Journal of Neuroscience·T BlasiakM H Lewandowski
Jul 26, 2007·The European Journal of Neuroscience·Boyoung LeeKarl Obrietan
Dec 22, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·J D GlassN Mrosovsky
Jul 21, 2005·The European Journal of Neuroscience·Andrew N Coogan, Hugh D Piggins
Jan 14, 2021·Neuroscience and Biobehavioral Reviews·Pawan Kumar JhaEtienne Challet
Jul 22, 2019·Physiology & Behavior·Thijs J WalbeekMichael R Gorman
Sep 28, 1998·Brain Research. Molecular Brain Research·P J Larsen, P Kristensen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.