Cellular components of subretinal membranes in proliferative vitreoretinopathy.

Eye
P HiscottZ Gregor

Abstract

To determine the cellular composition of subretinal membranes in proliferative vitreoretinopathy, surgically excised membranes were studied using electron microscopic and immunohistochemical procedures. Light microscopic immunohistochemistry was found to be superior to conventional electron microscopy as a means of evaluating the relative contributions of retinal pigment epithelium and glia to subretinal membranes. The cells of subretinal membranes chiefly comprised retinal pigment epithelium while glial cells were either absent or contributed only a minor component. It is proposed that the clinical properties of subretinal membranes in proliferative vitreoretinopathy derive from their retinal pigment epithelial cell element.

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Citations

Jun 1, 1994·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·S SeregardL Berglin
Mar 22, 2002·Progress in Retinal and Eye Research·J Carlos PastorFrancisco Martín
Feb 5, 1999·Progress in Retinal and Eye Research·P HiscottI Grierson
Jul 9, 2002·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Wen-Chuan WuDan-Ning Hu
Mar 22, 2003·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Wen-Chuan WuHan-Yi Tseng
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Jan 1, 1993·Ophthalmology·D G CharterisI Grierson
May 7, 2013·Survey of Ophthalmology·Justus G GarwegMarkus Halberstadt
Oct 17, 2007·American Journal of Ophthalmology·Christopher G KissMichaela Velikay-Parel
Jun 17, 1998·Experimental Eye Research·C CapeánsM Sanchez-Salorio
Jul 27, 2010·Biochemical and Biophysical Research Communications·Michiya TakadaTsutomu Hirano
May 10, 2019·Communications Biology·Lauren SchiffTimothy A Blenkinsop
Dec 9, 2010·European Journal of Ophthalmology·Jörg Winkler, Hans Hoerauf
Jan 12, 2020·Communications Biology·Lauren SchiffTimothy A Blenkinsop

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