Cellular connections, microenvironment and brain angiogenesis in diabetes: Lost communication signals in the post-stroke period

Brain Research
Adviye ErgulSusan C Fagan

Abstract

Diabetes not only increases the risk but also worsens the motor and cognitive recovery after stroke, which is the leading cause of disability worldwide. Repair after stroke requires coordinated communication among various cell types in the central nervous system as well as circulating cells. Vascular restoration is critical for the enhancement of neurogenesis and neuroplasticity. Given that vascular disease is a major component of all complications associated with diabetes including stroke, this review will focus on cellular communications that are important for vascular restoration in the context of diabetes. This article is part of a Special Issue entitled SI: Cell Interactions In Stroke.

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Citations

Apr 12, 2015·Brain Research·Turgay Dalkara, Luis Alarcon-Martinez
Sep 7, 2016·Journal of Diabetes and Its Complications·Nele WarmkeRichard M Cubbon
Feb 6, 2017·Circulation Research·Xiaoming HuFrank M Faraci
Sep 10, 2019·Stroke; a Journal of Cerebral Circulation·Turgay Dalkara
Aug 9, 2020·Aging and Disease·Wei-Xing MaLiang-Jun Yan

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