Cellular contributions to glomerular size-selectivity

Kidney International
W M Deen

Abstract

The glomerular capillary wall permits free passage of low-molecular-weight solutes, while severely restricting large proteins. Although both cell layers (endothelium and epithelium) almost certainly contribute to this size-selectivity, their relative importance has been difficult to assess. The finding by Rippe et al. of an inverse relationship between the sieving coefficient of Ficoll and glomerular filtration rate sheds light on this.

References

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Nov 17, 2004·The Journal of Clinical Investigation·William M Deen

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Citations

Jun 1, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·K C KadakiaC L Loprinzi
Mar 15, 2011·European Heart Journal·Jean-Baptiste MichelGerard Pasterkamp
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Jan 16, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ellen NevenVeerle Persy
May 8, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ryohei YamamotoHiromi Rakugi
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Dec 17, 2021·Frontiers in Medicine·Barbara J BallermannBörje Haraldsson

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