PMID: 109251Jan 1, 1978

Cellular control of growth in cultures of Tetrahymena. 3. The influence of Fe-medium and aeration on cellular ultrastructure

K H Andersson


Cultures of Tetrahymena pyriformis were grown with and without the addition of Fe and with no aeration. The same cultures were used both for determinations of the cellular Fe and Ca concentrations and the exchange of Ca (reported earlier), and for the ultrastructural study. In all cultures there was an increase in rounded, tubuli-deficient mitochondria at the transition to the prestationary growth phase. In the non-aerated culture (high cellular Fe content) these changes were less marked. In the Fe-deficient culture, however, these mitochondrial changes were seen as early as the late exponential growth phase, and tubuli-degeneration then increased during the prestationary growth phase. In this culture an irregular infolding of the outer mitochondrial membranes occurred. These changes are discussed in correlation with cytochromes, Fe-dependent desaturation of fatty acids, and high Ca concentration (non-aerated cells). During the prestationary growth phase of the non-aerated culture there was a marked increase in the amount of mitochondrial tubuli. In the organelles identified as peroxisomes there was, in all the cultures, an increased granular density of the matrix at the transition to the prestationary growth phase (in the Fe-d...Continue Reading

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