Cellular, humoral, and histopathologic analysis in rats implanted with orthodontic nickel brackets

The Angle Orthodontist
Cássio Vicente PereiraLuciano José Pereira

Abstract

To determine the immune response related to nickel and nickel-free orthodontic appliances using cellular (total and differential leukocytes) and humoral (IgA) quantification. Thirty-five Wister rats were randomly distributed into three groups (A, B, and C). In the A group, the animals were subdivided into three subgroups (A1: control, without brackets; A2: nickel-free brackets; and A3: nickel brackets) with seven animals in each group; the animals were sacrificed after 14 days. Groups B and C received only nickel brackets and were kept for 14 days. After this period, the implants were removed and the rats were sacrificed. In group B, the animals were sacrificed 2 days after the appliance removal (16 days in total); and in group C, the animals were sacrificed 7 days after the brackets removal (21 days in total). Total and differential leukocyte number, IgA quantification and histopathologic analysis were done. Histopathologic analysis of subcutaneous tissue related to the orthodontic brackets was done as well. There were significant differences between the number of leukocytes for the nickel-implanted animals and the nickel-free and control groups after 14 days of implantation (P < .05). However, there was no significant differe...Continue Reading

References

May 6, 1978·Lancet·I M RoittL J Nineham
Jul 4, 1977·Biochimica Et Biophysica Acta·C A Carvalho, A P Carvalho
Feb 1, 1992·European Journal of Orthodontics·M R GrimsdottirA Kullmann
Aug 1, 1990·European Journal of Orthodontics·L Staerkjaer, T Menné
Oct 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·V M SandersE S Vitetta
Apr 1, 1989·The Journal of the American Dental Association·C L DunlapB F Barker
Mar 1, 1987·Contact Dermatitis·H SchubertE Prater
Aug 1, 1988·The Journal of Experimental Medicine·R Fernandez-BotranE S Vitetta
Mar 1, 1986·American Journal of Orthodontics·M K Asgharnia, W A Brantley
May 1, 1994·Dental Materials : Official Publication of the Academy of Dental Materials·J C WatahaZ Sun
Jan 1, 1993·Annales de dermatologie et de vénéréologie·N H Nielsen, T Menné
Feb 1, 1996·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·H KerosuoA Hensten-Pettersen
Jan 1, 1996·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·C QueredaF Baquero
Aug 1, 1997·Journal of Biomedical Materials Research·I C WatahaD N Fang
Jun 24, 1998·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·G R JansonM R de Freitas
Dec 23, 1998·Connective Tissue Research·C T HanksW T Butler
Jul 9, 1999·Immunology Letters·L H HoganM Sandor
Jul 9, 1999·Journal of Biomedical Materials Research·J C WatahaM Ghazi
Feb 22, 2002·Journal of Oral Rehabilitation·J C WatahaS Bouillaguet
Jul 2, 2003·Journal of Orthodontics·G Rahilly, N Price
Jul 18, 2003·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·Marcelo MarigoLucia Fraga Alves-Oliveira
Oct 6, 2005·Trends in Cell Biology·Paul Martin, S Joseph Leibovich
Jan 13, 2006·Dental Materials : Official Publication of the Academy of Dental Materials·James C SetcosNairn H F Wilson
Feb 7, 2008·The Angle Orthodontist·Rodrigo Matos de Souza, Luciane Macedo de Menezes

❮ Previous
Next ❯

Citations

Aug 27, 2009·The Angle Orthodontist·Camila Alessandra PazziniLuciano José Pereira
Jul 23, 2016·Archives of Oral Biology·Fundagul BilgicYazgi Ay
Mar 2, 2011·Brazilian Oral Research·Camila Alessandra PazziniSaul Martins Paiva

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basophils

Basophils are myeloid cells with a high affinity IgE receptor and is involved in inflammatory responses during allergy. Discover the latest research on Basophils here.

Related Papers

Dental Materials : Official Publication of the Academy of Dental Materials
James C SetcosNairn H F Wilson
American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics
Luciana Borges RetamosoHugo Mitsuo Silva Oshima
American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics
Maria Francesca SfondriniCatherine Klersy
American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics
Heidi M Kerosuo, Jon E Dahl
Nederlands tijdschrift voor tandheelkunde
R L J LeenenC Katsaros
© 2021 Meta ULC. All rights reserved