Abstract
Immunoreactivity for the facilitated glucose transporter 1 (GLUT-1) has been found in the cochlear stria vascularis, but whether the strial marginal cells are immunopositive for GLUT-1 remains uncertain. To determine the cellular localization of GLUT-1 and to clarify the glucose pathway in the stria vascularis of rats and guinea pigs, immunohistochemistry was performed on sections, dissociated cells, and whole-tissue preparations. Immunoreactivity for GLUT-1 in sections was observed in the basal side of the strial tissue and in capillaries in both rats and guinea pigs. However, the distribution of the positive signals within the guinea pig strial tissue was more diffuse than that in rats. Immunostaining of dissociated guinea pig strial cells revealed GLUT-1 in the basal cells and capillary endothelial cells, but not in the marginal cells. These results indicated that GLUT-1 was not expressed in the marginal cells, and that another isoform of GLUT was probably expressed in these cells. Three-dimensional observation of whole-tissue preparations demonstrated that cytoplasmic prolongations from basal cells extended upward to the apical surface of the stria vascularis from rats and guinea pigs, and that the marginal cells were surro...Continue Reading
References
Nov 1, 1978·The Laryngoscope·D C MarcusN Y Marcus
Sep 28, 1978·Archives of Oto-rhino-laryngology·D C MarcusN Y Marcus
Oct 1, 1978·Hearing Research·J PrazmaD Ascher
Mar 1, 1989·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·T IwanoY Tashiro
Jan 1, 1985·Hearing Research·D C MarcusR Thalmann
Dec 1, 1972·The Laryngoscope·R ThalmannI Thalmann
Feb 1, 1982·Hearing Research·J KambayashiR Thalmann
Apr 1, 1995·Hearing Research·P WangemannD C Marcus
Feb 1, 1995·Anatomy and Embryology·T KikuchiJ C Adams
Jul 1, 1994·Hearing Research·B A Schulte, K P Steel
Dec 1, 1993·Hearing Research·M ItoB A Schulte
Jul 1, 1996·Hearing Research·K NakazawaB A Schulte
Jan 1, 1997·Connective Tissue Research·H Hashimoto, M Kusakabe
Feb 3, 1998·Hearing Research·S Takeuchi, M Ando
Jul 9, 1998·Neuroscience Letters·S Takeuchi, M Ando
Jul 15, 1998·Cell and Tissue Research·S Takeuchi, M Ando
Nov 3, 1998·Cell and Tissue Research·J LautermannE Winterhager
Jun 25, 1999·Acta Oto-laryngologica·T YoshiharaT Ishii
Oct 28, 1999·Brain Research·A XiaT Takasaka
Nov 11, 1999·Cell and Tissue Research·M Ando, S Takeuchi
Oct 29, 2000·Biophysical Journal·S TakeuchiA Kakigi
Apr 18, 2001·Brain Research·A XiaK Ikeda
May 4, 2001·Hearing Research·S TakeuchiA Kakigi
Jan 15, 2002·American Journal of Physiology. Cell Physiology·Daniel C MarcusPaulo Kofuji
Feb 6, 2003·The British Journal of Nutrition·I Stuart Wood, Paul Trayhurn
Sep 25, 2004·Journal of Cellular Physiology·Maria L MachedaJames D Best
Citations
Sep 13, 2008·Histochemistry and Cell Biology·Toshihiro SuzukiMasahito Oyamada
Jan 30, 2016·Acta Oto-laryngologica·Mattia Carraro, Robert V Harrison
Dec 25, 2010·Neuroscience Letters·Midori EdamatsuMotonori Ando
Dec 29, 2015·Hearing Research·Mattia CarraroRobert V Harrison
Oct 1, 2014·PloS One·Meiyan JiangPeter S Steyger
Oct 31, 2016·Hearing Research·Daniel T MeehanDominic Cosgrove
Apr 2, 2014·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Olubunmi Victoria AkinpeluSam J Daniel
Jun 1, 2018·Neural Plasticity·Xiao-Ting ChengNing Yu
Oct 12, 2017·Frontiers in Molecular Neuroscience·Mitsuo P SatoHiroshi Hibino
Oct 25, 2017·Frontiers in Cellular Neuroscience·Meiyan JiangPeter S Steyger
May 23, 2019·Audiology & Neuro-otology·Nathan HuerzelerDaniel Bodmer