PMID: 11315951Apr 24, 2001Paper

Cellular proliferation in bovine luteal tissues of different reproductive states as demonstrated by Ki-67 immunocytochemistry

Italian Journal of Anatomy and Embryology = Archivio Italiano Di Anatomia Ed Embriologia
A Boos

Abstract

Luteal tissue specimens of corpora lutea of oestrous cycle and pregnancy, post partum corpora lutea, and of luteinised follicular cysts of cows were harvested at slaughter. Cellular proliferation was examined employing Ki-67 immunocytochemistry. Ki-67 immunoreactivities could mainly be demonstrated within the nuclei of the theca interna and theca externa derived cell populations of cyclic corpora lutea. These cells obviously differentiated into vascular cells, connective tissue cells and small luteal cells. Proliferative activity was strongest in young corpora lutea and markedly reduced in the mature ones. During involution of corpora lutea of oestrous cycle Ki-67-positive cells were mainly found in vascular walls and connective tissue districts. Luteinised follicular cysts closely resembled cyclic corpora lutea. Corpora lutea of pregnancy exhibited foci of immunopositive cells close to blood vessels and connective tissue septae during whole gestation. Post partal luteal involution was characterised by Ki-67-positive cells within vascular walls and the surrounding stroma. Results suggest that luteal cellular proliferation is restricted mainly to theca interna-derived cells, which may differentiate to stromal cells and parenchym...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.