PMID: 14418248Jul 1, 1960Paper

Cellular proliferation of intestinal epithelia in the rat two months after partial resection of the ileum

The Journal of Biophysical and Biochemical Cytology
M R LORAN, T L ALTHAUSEN

Abstract

Sprague-Dawley rats subjected 2 months previously to partial resection (10 per cent) of the small intestine and their controls were injected with tritiated thymidine and sacrificed at 2 and 23 hours. Segments of the duodenum, jejunum, and ileum were autoradiographed, and the migration of the labelled cells during the period between 2 and 23 hours was measured with an eyepiece micrometer. The cells had migrated 35, 42, and 34 per cent of the total distance from the crypts to the tips of the villi in the control segments of duodenum, ileum, and jejunum respectively, and 43, 90, and 82 per cent, respectively, in similar segments from resected animals. The rate of migration in the portion of the intestine remaining after resection was approximately three times the normal rate in the ileum, twice the normal rate in the jejunum, and showed an increase of one-third in the duodenum. These results demonstrate that the rate of cell renewal is considerably greater in the remaining portion of the intestine of resected animals than in normal intestine. The increased rate of migration after resection, together with the increase in the height of the villi, resulted in an increase in the rate of cell renewal amounting to 141 per cent in the il...Continue Reading

References

May 1, 1959·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M AMANOC P LEBLOND

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Citations

Apr 28, 1964·Zeitschrift für Zellforschung und mikroskopische Anatomie· VAN LENNEPE
Jul 1, 1977·The American Journal of Digestive Diseases·F T McDermott, B Roudnew
Aug 31, 1979·World Journal of Surgery·L R Johnson
Jan 1, 1965·The American Journal of Digestive Diseases·M E CONRADW H CROSBY
Mar 1, 1969·The American Journal of Digestive Diseases·I Skála, V Konrádová
Apr 1, 1967·The American Journal of Digestive Diseases·G E ShambaughW R Beisel
Nov 2, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Jennifer A LeinickeBrad W Warner
Nov 1, 1968·Developmental Biology·R D Grey
Nov 1, 1980·The Journal of Surgical Research·E GatonB Man
Jan 1, 1986·Comparative Biochemistry and Physiology. A, Comparative Physiology·D W Skagen, K J Andersen
Nov 26, 1970·The New England Journal of Medicine·J D GardnerL Laster
Jun 22, 1978·The New England Journal of Medicine·R C Williamson
Jan 1, 1968·Postgraduate Medical Journal·C C Booth
May 1, 2001·Seminars in Pediatric Surgery·D P O'BrienB W Warner
Feb 6, 2004·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·J Collantes PérezC Verástegui Escolano
Nov 1, 1993·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·S K SaxenaJ G Sharp
Jan 1, 1978·Scandinavian Journal of Gastroenterology·Z H Woo, K Nygaard
Oct 31, 2007·Gastrointestinal Endoscopy Clinics of North America·Alan L Buchman
Jun 11, 2011·The Journal of Surgical Research·Michael S KatzMarshall Z Schwartz
Nov 4, 2010·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Koh-En YamauchiKoun Yamauchi
Jul 1, 1968·American Journal of Surgery·Z LanskyL H Stahlgren
Nov 1, 1985·Medical Hypotheses·G Zajicek
Nov 1, 1972·Metabolism: Clinical and Experimental·E Hietanen, O Hänninen
Jan 1, 1979·Medical Hypotheses·G Zajicek
Dec 1, 1969·The British Journal of Surgery·S WapnickA G Cox
Jul 7, 2007·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Valéria Cristina Soares FurtadoAntonio Carlos Iglesias
May 1, 1973·Cell and Tissue Kinetics·P J Tutton
Jan 1, 1963·The Journal of Pathology and Bacteriology·B F FELLR M CAMPBELL
Sep 23, 2014·Drug Metabolism and Disposition : the Biological Fate of Chemicals·Adam S DarwichAmin Rostami-Hodjegan
Feb 20, 1969·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·C P SigdestadD L Levine
Jan 1, 2004·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·J Collantes PérezC Verástegui Escolano
Jan 1, 1968·Progress in Biophysics and Molecular Biology·L F Lamerton, G G Steel
Oct 25, 1972·Biochimica Et Biophysica Acta·H Nakayama, E Weser

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