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Cellular reprogramming for successful CNS axon regeneration is driven by a temporally changing cast of transcription factors

Scientific Reports

Oct 4, 2019

Sumona P DharaAva J Udvadia

Abstract

In contrast to mammals, adult fish display a remarkable ability to fully regenerate central nervous system (CNS) axons, enabling functional recovery from CNS injury. Both fish and mammals normally undergo a developmental downregulation of axon growth activity as neurons mature. Fish are...read more

Mentioned in this Paper

Vertebrates
Biochemical Pathway
Injury of Central Nervous System
Cell Injury
Genes
Advice
Regulation of Biological Process
Transcription, Genetic
Neurons
Brain
7
11
Paper Details
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Cellular reprogramming for successful CNS axon regeneration is driven by a temporally changing cast of transcription factors

Scientific Reports

Oct 4, 2019

Sumona P DharaAva J Udvadia

PMID: 31578350

DOI: 10.1038/s41598-019-50485-6

Abstract

In contrast to mammals, adult fish display a remarkable ability to fully regenerate central nervous system (CNS) axons, enabling functional recovery from CNS injury. Both fish and mammals normally undergo a developmental downregulation of axon growth activity as neurons mature. Fish are...read more

Mentioned in this Paper

Vertebrates
Biochemical Pathway
Injury of Central Nervous System
Cell Injury
Genes
Advice
Regulation of Biological Process
Transcription, Genetic
Neurons
Brain
7
11

Similar Papers Found In These Feeds

Organ Regeneration

Regeneration in humans is the regrowth of tissues or organs in response to injury or damage. Discover the latest research on organ neuroregeneration here.

Nuclear Architecture

The 3-D organization of chromatin is an important factor in the regulation of gene expression. Find the latest research on nuclear architecture here.

Related Papers

Frontiers in Molecular Neuroscience

Epigenetic regulation of axon and dendrite growth

Frontiers in Molecular NeuroscienceMarch 10, 2012
Ephraim F Trakhtenberg, Jeffrey L Goldberg
Paper Details
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  • Citations1
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations1
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