Cellular uptake of β-carotene from protein stabilized solid lipid nanoparticles prepared by homogenization-evaporation method

Journal of Agricultural and Food Chemistry
Jiang YiFang Zhong

Abstract

With a homogenization-evaporation method, β-carotene (BC) loaded nanoparticles were prepared with different ratios of food-grade sodium caseinate (SC), whey protein isolate (WPI), or soy protein isolate (SPI) to BC and evaluated for their physiochemical stability, in vitro cytotoxicity, and cellular uptake by Caco-2 cells. The particle diameters of the BC loaded nanoparticles with 0.75% SC or 1.0% WPI emulsifiers were 75 and 90 nm, respectively. Mean particle diameters of three BC loaded nanoparticle nanoemulsions increased less than 10% at 4 °C while they increased more at 25 °C (10-76%) during 30 days of storage. The oxidative stability of BC loaded nanoparticles encapsulated by proteins decreased in the following order: SC > WPI > SPI. The retention rates of BC in nanoparticles were 63.5%, 60.5%, and 41.8% for SC, WPI, and SPI, respectively, after 30 days of storage at 25 °C. The BC's chemical stability was improved by increasing the concentration of protein. Both the rate of particle growth and the total BC loss at 25 °C were larger than at 4 °C. The color of BC loaded nanoparticles decreased with increasing storage in the dark without oxygen, similar to the decrease in BC content of nanoparticles at 4 and 25 °C. Almost no ...Continue Reading

References

Mar 7, 2003·Nature·Sean D Conner, Sandra L Schmid
Aug 3, 2006·Journal of Agricultural and Food Chemistry·Ana Lucía Vasquez-CaicedoReinhold Carle
May 20, 2011·Journal of Agricultural and Food Chemistry·Leonardo Cornacchia, Yrjo H Roos
Jan 1, 2004·Meat Science·Shai Barbut
Nov 23, 2011·Food & Function·David Julian McClements, Hang Xiao

❮ Previous
Next ❯

Citations

Dec 3, 2015·Journal of Agricultural and Food Chemistry·Jiang YiLiqing Zhao
Aug 26, 2015·Food Chemistry·Alison KamilC-Y Oliver Chen
Apr 8, 2015·Critical Reviews in Food Science and Nutrition·Jake McClements, David Julian McClements
Aug 16, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Małgorzata Geszke-Moritz, Michał Moritz
Sep 21, 2016·Critical Reviews in Food Science and Nutrition·Like MaoYanxiang Gao
Jul 12, 2017·Journal of Agricultural and Food Chemistry·Yuting FanWallace Yokoyama
Apr 9, 2019·Expert Opinion on Drug Delivery·Sajedehsadat MaghrebiPaul Joyce
Nov 7, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·A Ligia FocsanLowell D Kispert
Jul 6, 2018·Food & Function·Felipe RochaOdinei Hess Gonçalves
Feb 2, 2019·Food Science and Technology International = Ciencia Y Tecnología De Los Alimentos Internacional·Mitra Firoozy, Navideh Anarjan
Mar 21, 2019·Frontiers in Nutrition·Tanuka SenSunil Kumar Deshmukh
Dec 30, 2020·Food Chemistry·Larissa Santos AssunçãoItaciara Larroza Nunes
Jan 29, 2021·Comprehensive Reviews in Food Science and Food Safety·Seyed Mohammad Taghi Gharibzahedi, Brennan Smith
Apr 4, 2021·Antioxidants·Vaibhav Kumar MauryaSunil Pareek

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Landau-Kleffner Syndrome

Landau Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, or aphasia with convulsive disorder, is a rare childhood neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and an abnormal electroencephalogram. Discover the latest research on LKS here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

© 2021 Meta ULC. All rights reserved