Cellulose nanocrystals in cancer diagnostics and treatment.

Journal of Controlled Release : Official Journal of the Controlled Release Society
Ishaq LugoloobiYili Zhao

Abstract

Cancer is currently a major threat to public health, being among the principal causes of death to the global population. With carcinogenesis mechanisms, cancer invasion, and metastasis remaining blurred, cancer diagnosis and novel drug delivery approaches should be developed urgently to enable management and treatment. A dream break-through would be a non-invasive instantaneous monitoring of cancer initiation and progression to fast-track diagnosis for timely specialist treatment decisions. These innovations would enhance the established treatment protocols, unlimited by evasive biological complexities during tumorigenesis. It is therefore contingent that emerging and future scientific technologies be equally biased towards such innovations by exploiting the apparent properties of new developments and materials especially nanomaterials. CNCs as nanomaterials have undisputable physical and excellent biological properties that enhanced their interest as biomedical materials. This article therefore highlights CNCs utility in cancer diagnosis and therapy. Their extraction, properties, modification, in-vivo/in-vitro medical applications, biocompatibility, challenges and future perspectives are precisely discussed.

References

Jun 1, 1992·International Journal of Biological Macromolecules·J F RevolD G Gray
Nov 1, 1993·Journal of Biomedical Materials Research·S A AliD F Williams
Apr 1, 1953·Biochimica Et Biophysica Acta·S M MUKHERJEE, H J WOODS
Jan 15, 1950·Experientia·B G RANBY, E RIBI
Oct 24, 2007·Journal of the American Chemical Society·Shuping Dong, Maren Roman
Apr 29, 2008·Biomaterials·David F Williams
Nov 1, 2008·Cancer Research·Vincent T DeVita, Edward Chu
Mar 6, 2010·Chemical Reviews·Youssef HabibiOrlando J Rojas
Oct 6, 2010·ACS Applied Materials & Interfaces·Khaled A MahmoudJohn H T Luong
Jan 5, 2011·Chemosphere·Klaus KümmererWim Thielemans
Jan 19, 2011·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·J C O VillanovaR L Oréfice
May 14, 2011·Chemical Society Reviews·Robert J MoonJeff Youngblood
Aug 11, 2011·Macromolecular Bioscience·Tim LiebertThomas Heinze
Nov 30, 2011·Journal of Nanobiotechnology·Anil Mahapatro, Dinesh K Singh
May 5, 2012·Bioorganic & Medicinal Chemistry Letters·Nicolas DrogatVincent Sol
Nov 8, 2012·Bioresource Technology·Lirong TangXuerong Chen
Dec 25, 2012·Journal of Controlled Release : Official Journal of the Controlled Release Society·Sheva NaahidiP Chen
Aug 6, 2013·Journal of Biomedical Nanotechnology·Changyoon BaekSoong Ho Um
Aug 21, 2013·Biomacromolecules·Tiffany AbitbolEmily D Cranston
May 27, 2014·Colloids and Surfaces. B, Biointerfaces·Zahid HanifSoong Ho Um
Jun 11, 2014·Biomacromolecules·Rui M A DominguesRui L Reis
Oct 24, 2014·ACS Applied Materials & Interfaces·Vaishakhi MohantaSatish Patil
Dec 3, 2014·Carbohydrate Polymers·Assya BoujemaouiAnna Carlmark
Jul 15, 2015·Nanoscale·Zeinab HosseinidoustTheo G M van de Ven
Aug 1, 2015·Biomacromolecules·Laura ColomboBarbara La Ferla
Jan 8, 2016·Bioorganic & Medicinal Chemistry Letters·Gautier M A Ndong NtoutoumeVincent Sol
Jan 1, 2014·ACS Sustainable Chemistry & Engineering·Naveena YanamalaAnna A Shvedova
Apr 26, 2016·Expert Opinion on Drug Delivery·Rajesh SunaseeKarina Ckless
Jun 15, 2016·Journal of Controlled Release : Official Journal of the Controlled Release Society·Sourav Bhattacharjee
Jul 31, 2016·Carbohydrate Polymers·You Wei ChenSiew-Moi Phang
Aug 16, 2016·Journal of Pharmaceutical Sciences·Siew Yong TeoAllan G A Coombes
Aug 26, 2016·Journal of Toxicology and Environmental Health. Part a·Mariana T FarcasAnna A Shvedova
Dec 3, 2016·Journal of Nanobiotechnology·C EndesM J D Clift

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.