Center volume and post-transplant survival among adults with congenital heart disease

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Jonathan N MenachemSandip Zalawadiya

Abstract

The number of adult congenital heart disease (ACHD) patients requiring heart transplantation (HT) continues to grow, and if they survive the first year after transplant, their long-term survival is at least equivalent to non-ACHD patients. The 1-year survival of ACHD patients with HT remains lower than non-ACHD patients. We evaluated the affect of transplant center volume on 1-year survival of ACHD patients. We analyzed United Network of Organ Sharing patients (age ≥18 years) who underwent their first orthotopic HT between January 1, 2000, and December 31, 2015, to assess the association between transplant center volume and 1-year survival of ACHD patients. We identified 827 ACHD patients at 113 centers who underwent HT during the study period. The average age of the recipients and donors was 36 ± 13 years (60% men and 84% Caucasian) and 28 ± 11 (63% men and 66% Caucasian), respectively. Of the ACHD patients undergoing HT, 27% (n = 60) were done at low-volume centers, 30% (n = 10) were reported at high-volume centers, and the remaining (n = 43) were at medium-volume centers. A total of 96 patients died within 30 days, including 37 (16.7%) at low-volume, 37 (10.2%) at medium-volume, and 22 (9.0%) at high-volume centers (p = 0.01...Continue Reading

Citations

Jun 11, 2020·Circulation. Cardiovascular Interventions·Alexander R Opotowsky, Gary D Webb
Aug 2, 2020·The Annals of Thoracic Surgery·Laura SeeseArman Kilic
Dec 16, 2019·JACC. Heart Failure·Jonathan N MenachemJoAnn Lindenfeld
Aug 26, 2020·Journal of Cardiothoracic and Vascular Anesthesia·Aisling McMahonMichael Griffin
Nov 27, 2019·Journal of Cardiac Failure·Amit IyengarPavan Atluri
Sep 20, 2020·The Annals of Thoracic Surgery·Atsushi KainumaKoji Takeda
May 10, 2021·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Stephen J DolgnerTodd F Dardas
Mar 31, 2020·The Journal of Thoracic and Cardiovascular Surgery·Daniel E ClarkJonathan N Menachem
Apr 14, 2020·The Journal of Thoracic and Cardiovascular Surgery·Yasuhiro Shudo, Katsuhide Maeda
Jul 10, 2021·Journal of the American Heart Association·Geoffrey D HuntleyAri M Cedars
Aug 10, 2021·Journal of Cardiac Surgery·Nicholas R HessArman Kilic
Aug 9, 2021·Clinical Transplantation·Angelo L de la RosaMichelle M Kittleson
Oct 5, 2021·Acta Cardiologica·Samuel BrulsJean-Olivier Defraigne
Dec 4, 2021·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Katia Bravo-JaimesAri Cedars

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Joshua C GrimmChristopher M Sciortino
The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Yamini KrishnamurthyChetan B Patel
© 2022 Meta ULC. All rights reserved