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Central action of WA-335-BS, a substance with peripheral antiserotonin and antihistaminic activity

Arzneimittel-Forschung

Nov 1, 1975

J KählingH Ballhause

PMID: 1050

Abstract

In rats and mice the serotonin and histamine antagonistic drug 9,10-dihydro-10-(1-methyl-4-piperidylidene)-9-anthrol (WA 335-BS) caused stronger central sedative effects than did cyproheptadine. WA 335-BS also displayed stronger activity against reserpine- and central tremorine-induced ...read more

Mentioned in this Paper

Histamine Measurement
Nervousness
Vigilance, Cortical
Behavior, Animal
Exertion
Serotonin Measurement
Anti-Anxiety Effect
Serotonin
Antihistamine [EPC]
Desire for Food
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Central action of WA-335-BS, a substance with peripheral antiserotonin and antihistaminic activity

Arzneimittel-Forschung

Nov 1, 1975

J KählingH Ballhause

PMID: 1050

DOI:

Abstract

In rats and mice the serotonin and histamine antagonistic drug 9,10-dihydro-10-(1-methyl-4-piperidylidene)-9-anthrol (WA 335-BS) caused stronger central sedative effects than did cyproheptadine. WA 335-BS also displayed stronger activity against reserpine- and central tremorine-induced ...read more

Mentioned in this Paper

Histamine Measurement
Nervousness
Vigilance, Cortical
Behavior, Animal
Exertion
Serotonin Measurement
Anti-Anxiety Effect
Serotonin
Antihistamine [EPC]
Desire for Food

Similar Papers Found In These Feeds

Antipsychotic Drugs

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here

Learning and Memory

Here is the latest research on neural and genetic circuits and mechanisms implicated in memory and learning, including discriminatory learning, conditioning, and psychophysiological habituation.

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Paper Details
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  • finger pointing at paper

    References currently unavailable

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