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Central action of WA-335-BS, a substance with peripheral antiserotonin and antihistaminic activity

Arzneimittel-Forschung

Nov 1, 1975

J KählingH Ballhause

PMID: 1050

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Abstract

In rats and mice the serotonin and histamine antagonistic drug 9,10-dihydro-10-(1-methyl-4-piperidylidene)-9-anthrol (WA 335-BS) caused stronger central sedative effects than did cyproheptadine. WA 335-BS also displayed stronger activity against reserpine- and central tremorine-induced ...read more

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  • Central action of WA-335-BS, a substance with peripheral antiserotonin and antihistaminic activity

    Arzneimittel-Forschung

    Nov 1, 1975

    J KählingH Ballhause

    PMID: 1050

    DOI:

    Abstract

    In rats and mice the serotonin and histamine antagonistic drug 9,10-dihydro-10-(1-methyl-4-piperidylidene)-9-anthrol (WA 335-BS) caused stronger central sedative effects than did cyproheptadine. WA 335-BS also displayed stronger activity against reserpine- and central tremorine-induced ...read more

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