PMID: 1202599Nov 1, 1975Paper

Central and peripheral neural respiratory activity in the mature sheep foetus and newborn lamb

Respiration Physiology
E BystrzyckaM J Purves

Abstract

Activity from respiratory neurones in the medulla, the phrenic and intercostal nerves was recorded in 25 foetal sheep, exteriorized a few days before term from ewes given a spinal anaesthetic, and from nine newborn lambs, anaesthetized with an allobarbitone-urethane mixture. In 12 foetuses, there was little or no sustained respiratory activity, central activity consisting of tonically discharging expiratory and other neurones and silent inspiratory neurones. In the remaining 13 foetuses, respiratory activity was periodic or continuous and it was possible to confirm that the motor component of the respiratory reflex was mature, that apnoea was not due to medullary depression, that foetal respiration was unaffected by chemoreceptor stimulation, by noise, by light, by electrical stimulation of the sciatic nerve and only slightly by inflation or deflation of the lungs. All these stimuli were effective shortly after birth. Occlusion of the umbilical cord caused poorly sustained gasps in the "non-breathing" foetuses and in the "breathing" foetuses, abolition of inspiratory and expiratory activity in the medulla and the onset of gasps and flattening of the electro-corticogram. Rhythmic respiration resumed after release of the cord wit...Continue Reading

References

Jan 1, 1972·The Journal of Physiology·G S DawesR T Richards
Oct 1, 1966·American Journal of Diseases of Children·H S HarnedC K Holmes
Dec 1, 1967·Respiration Physiology·P C Tang
Aug 1, 1964·The Journal of Physiology·L M MENDELL, P D WALL

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Citations

Nov 1, 1980·Pflügers Archiv : European journal of physiology·S IoffeV Chernick
May 1, 1980·Respiration Physiology·R HardingM E McClelland
Feb 1, 1981·American Family Physician·J Hobbs
Sep 1, 1981·Respiration Physiology·I R MossE M Scarpelli
Jul 16, 1991·Brain Research. Developmental Brain Research·J M Bissonnette, M Reddington
Nov 8, 2002·Acta Obstetricia Et Gynecologica Scandinavica·Seong-Won MinChong-Soo Kim
Oct 1, 1986·Clinical Otolaryngology and Allied Sciences·D J Willatt
Dec 16, 1978·British Medical Journal
Sep 18, 1992·Brain Research·G B Richerson, P A Getting
Jul 1, 1982·Acta paediatrica Scandinavica·M J Purves
May 30, 2003·Journal of Perinatology : Official Journal of the California Perinatal Association·Luigi MatturriLino Rossi
Apr 30, 1999·Physiological Reviews·G Hilaire, B Duron
Sep 8, 1979·The Medical Journal of Australia·D J ReadS Beal
Jan 29, 2005·International Journal of Experimental Pathology·Anna Maria LavezziLuigi Matturri

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