Central auditory neurons have composite receptive fields

Proceedings of the National Academy of Sciences of the United States of America
Andrei S Kozlov, Timothy Q Gentner

Abstract

High-level neurons processing complex, behaviorally relevant signals are sensitive to conjunctions of features. Characterizing the receptive fields of such neurons is difficult with standard statistical tools, however, and the principles governing their organization remain poorly understood. Here, we demonstrate multiple distinct receptive-field features in individual high-level auditory neurons in a songbird, European starling, in response to natural vocal signals (songs). We then show that receptive fields with similar characteristics can be reproduced by an unsupervised neural network trained to represent starling songs with a single learning rule that enforces sparseness and divisive normalization. We conclude that central auditory neurons have composite receptive fields that can arise through a combination of sparseness and normalization in neural circuits. Our results, along with descriptions of random, discontinuous receptive fields in the central olfactory neurons in mammals and insects, suggest general principles of neural computation across sensory systems and animal classes.

References

Dec 3, 2002·Bio Systems·Manuel A Sánchez-Montañés, Tim C Pearce
Mar 10, 2004·Neural Computation·Tatyana SharpeeWilliam Bialek
Feb 24, 2006·Nature·Evan C Smith, Michael S Lewicki
Jul 18, 2006·Current Opinion in Neurobiology·Frédéric E Theunissen, Sarita S Shaevitz
Jul 29, 2006·Science·G E Hinton, R R Salakhutdinov
Aug 18, 2006·Journal of Neurophysiology·Adrienne L FairhallMichael J Berry
Aug 7, 2008·The Journal of the Acoustical Society of America·Timothy Q Gentner
Feb 17, 2009·Proceedings of the National Academy of Sciences of the United States of America·Amir GlobersonNaftali Tishby
Mar 7, 2009·PLoS Computational Biology·Taffeta M Elliott, Frédéric E Theunissen
Sep 26, 2009·Neuron·Dan D Stettler, Richard Axel
Jan 29, 2010·Journal of Neurophysiology·Jason V Thompson, Timothy Q Gentner
Aug 17, 2010·Nature Neuroscience·Spencer L Smith, Michael Häusser
Dec 24, 2010·Nature·Kazunari MiyamichiLiqun Luo
May 4, 2011·Annals of the New York Academy of Sciences·Ann B ButlerHarvey J Karten
Nov 3, 2011·PLoS Computational Biology·Jeffrey D FitzgeraldTatyana O Sharpee
Oct 27, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·C Daniel Meliza, Daniel Margoliash
Dec 14, 2012·Nature Reviews. Cancer·Samy A F Morad, Myles C Cabot
Apr 26, 2013·Nature·Sophie J C CaronRichard Axel
May 21, 2013·Nature·Mattia RigottiStefano Fusi
Jul 16, 2013·Neuron·David M Schneider, Sarah M N Woolley
Dec 20, 2013·Journal of Neurophysiology·Andrei S Kozlov, Timothy Q Gentner
Aug 27, 2014·Neuron·Baktash Babadi, Haim Sompolinsky
Nov 12, 2014·Proceedings of the National Academy of Sciences of the United States of America·Zeyuan Allen-ZhuNir Shavit
Jan 24, 2015·Neural Networks : the Official Journal of the International Neural Network Society·Ian J GoodfellowYoshua Bengio

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Citations

Oct 26, 2016·Current Biology : CB·Joerg T Albert, Andrei S Kozlov
May 3, 2018·Journal of Neurophysiology·Johan Westö, Patrick J C May
Jun 19, 2018·ELife·Yosef SingerNicol S Harper
Jan 23, 2019·PLoS Computational Biology·Debmalya Chakrabarty, Mounya Elhilali
Jan 29, 2019·PLoS Computational Biology·Margot C Bjoring, C Daniel Meliza
Jan 18, 2019·PLoS Computational Biology·Abdul-Saboor SheikhJörg Lücke
Dec 9, 2017·Neural Computation·Wiktor Młynarski, Josh H McDermott
Sep 27, 2019·PLoS Computational Biology·Julie E Elie, Frédéric E Theunissen
Oct 23, 2018·F1000Research·Andrew J KingBen D B Willmore
Mar 18, 2020·Frontiers in Neuroscience·John HermizVikash Gilja
May 7, 2019·PLoS Computational Biology·Monzilur RahmanNicol S Harper
Oct 19, 2019·PLoS Computational Biology·Mateo Lopez EspejoStephen V David
Nov 23, 2019·Proceedings of the National Academy of Sciences of the United States of America·Wiktor Młynarski, Josh H McDermott
Dec 22, 2020·Frontiers in Neuroscience·Nicolas M AdreaniAndries Ter Maat
Nov 15, 2020·Science Advances·K YuF E Theunissen
Jul 12, 2017·Neuroscience·Craig A Atencio, Tatyana O Sharpee

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