Central blood pressure and chronic kidney disease

World Journal of Nephrology
Yoichi OhnoTsuneo Takenaka

Abstract

In this review, we focused on the relationship between central blood pressure and chronic kidney diseases (CKD). Wave reflection is a major mechanism that determines central blood pressure in patients with CKD. Recent medical technology advances have enabled non-invasive central blood pressure measurements. Clinical trials have demonstrated that compared with brachial blood pressure, central blood pressure is a stronger risk factor for cardiovascular (CV) and renal diseases. CKD is characterized by a diminished renal autoregulatory ability, an augmented direct transmission of systemic blood pressure to glomeruli, and an increase in proteinuria. Any elevation in central blood pressure accelerates CKD progression. In the kidney, interstitial inflammation induces oxidative stress to handle proteinuria. Oxidative stress facilitates atherogenesis, increases arterial stiffness and central blood pressure, and worsens the CV prognosis in patients with CKD. A vicious cycle exists between CKD and central blood pressure. To stop this cycle, vasodilator antihypertensive drugs and statins can reduce central blood pressure and oxidative stress. Even in early-stage CKD, mineral and bone disorders (MBD) may develop. MBD promotes oxidative stre...Continue Reading

References

Apr 12, 1984·Nature·T M GriffithA H Henderson
Nov 1, 1994·The American Journal of Physiology·T TakenakaL G Navar
Jul 21, 1998·Journal of the American College of Cardiology·S ThorneJ E Deanfield
Jan 25, 2000·American Journal of Nephrology·K HidaH Makino
May 16, 2000·The Journal of Physiology·I B WilkinsonD J Webb
Jun 29, 2002·Circulation Research·Rodger LoutzenhiserLisa Chilton
Jun 17, 2004·Circulation·Jean Davignon
Sep 24, 2004·Atherosclerosis·Tsuneo TakenakaHiromichi Suzuki
Sep 29, 2004·Hypertension·Anil K Bidani, Karen A Griffin
Mar 9, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Ming-Cheng WangJeng-Jong Huang
Mar 18, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Tsuneo Takenaka, Hiromichi Suzuki
Jul 19, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Sarah A HopeJames D Cameron
Aug 20, 2005·American Journal of Nephrology·Tsuneo TakenakaHiromichi Suzuki
Sep 29, 2005·American Journal of Physiology. Renal Physiology·Tsuneo TakenakaHiromichi Suzuki
May 19, 2007·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Kenji TakazawaAkira Yamashina
Aug 4, 2007·Kidney International. Supplement·E Schleicher, U Friess
Apr 24, 2009·Clinical and Experimental Hypertension : CHE·Tsuneo TakenakaHiromichi Suzuki
Jul 17, 2009·Arteriosclerosis, Thrombosis, and Vascular Biology·Paul M Vanhoutte
Sep 2, 2009·Hypertension·James E SharmanThomas H Marwick
Mar 17, 2010·Lancet Neurology·Peter M RothwellUNKNOWN ASCOT-BPLA and MRC Trial Investigators
Nov 30, 2010·Cardiology Research and Practice·Tsuneo TakenakaHiromichi Suzuki
Jan 18, 2011·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Takatoshi KakutaAkira Saito
Jun 28, 2011·Clinical and Experimental Hypertension : CHE·Tsuneo TakenakaHiromichi Suzuki
Oct 12, 2011·The Journal of Clinical Investigation·Christian FaulMyles Wolf
Jan 13, 2012·Journal of Hypertension·Tsuneo TakenakaHiromichi Suzuki
May 9, 2012·Clinical and Experimental Hypertension : CHE·Tsuneo TakenakaHiromichi Suzuki
Jun 29, 2012·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Tsuneo TakenakaHiromichi Suzuki
Jan 10, 2013·The Journal of Clinical Investigation·Jakob VoelklFlorian Lang
Jan 8, 2014·International Journal of Hypertension·Tsuneo TakenakaHiromichi Suzuki
Jan 11, 2014·Stroke; a Journal of Cerebral Circulation·Alastair John Stewart Webb, Peter Malcolm Rothwell
May 23, 2014·Cardiorenal Medicine·Guanghong JiaJames R Sowers
May 24, 2014·Journal of the American Society of Nephrology : JASN·Yuan YingBabu J Padanilam
May 27, 2014·Lancet·Alberto OrtizUNKNOWN Board of the EURECA-m Working Group of ERA-EDTA
Aug 13, 2014·European Heart Journal·Annie HerbertUNKNOWN Reference Values for Arterial Measurements Collaboration

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Citations

Feb 25, 2018·Clinical Journal of the American Society of Nephrology : CJASN·Mahboob RahmanUNKNOWN CRIC Study Investigators
Oct 6, 2016·Molecular and Clinical Oncology·Alphons J M VermorkenYali Cui
Oct 17, 2020·American Journal of Physiology. Heart and Circulatory Physiology·Jorge Mariscal-HaranaJordi Alastruey

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