Central cord syndrome of cervical spinal cord injury: widespread changes in muscle recruitment studied by voluntary contractions and transcranial magnetic stimulation

Experimental Neurology
N AlexeevaB Calancie

Abstract

Muscle recruitment after central cord syndrome (CCS), a cervical spinal cord injury leading to a weaker motor function in the upper limbs versus the lower limbs, was examined in 14 individuals by means of voluntary muscle contractions and transcranial magnetic stimulation (TMS). Previously obtained data from able-bodied (AB) and non-CCS spinal cord injured subjects were used for comparison. Surface EMG was recorded from as many as six pairs of affected muscles. Individual muscle EMG activity was scored from 0 to 5. Cortical stimulation was applied while subjects maintained a weak contraction in each muscle. When CCS subjects attempted to produce a maximal voluntary contraction of an isolated muscle, this frequently resulted in cocontraction of nonsynergists in the same limb or/and in other limbs. Although the EMG scores in both upper and lower extremity muscles improved within postinjury time, in general, the lower extremity muscles, particularly the distal ones, demonstrated better recovery than the upper extremity muscles. CCS and AB subjects showed a similar high probability of "well-defined" responses to TMS (amplitude >150 microV) in all studied muscles. In contrast, latencies to TMS-evoked motor responses were prolonged b...Continue Reading

References

Jan 1, 1992·Journal of Neurology, Neurosurgery, and Psychiatry·B BrouwerP Ashby
Jan 1, 1992·Neuroradiology·R M QuencerM Norenberg
Oct 1, 1991·Electroencephalography and Clinical Neurophysiology·P D ThompsonC D Marsden
May 1, 1988·Electroencephalography and Clinical Neurophysiology·R BeneckeB Conrad
Jun 1, 1988·Electroencephalography and Clinical Neurophysiology·C J De Luca, R Merletti
Jul 1, 1989·The Journal of Physiology·P Ashby, M Wiens
Jun 1, 1989·Journal of the Neurological Sciences·S G Waxman
Sep 1, 1988·Journal of Neurosurgery·J M Piepmeier, N R Jenkins
Feb 1, 1985·Paraplegia·P Harris
Feb 1, 1993·Annals of Neurology·S G Waxman, J M Ritchie
Feb 1, 1995·Neurology·R A Macdonell, G A Donnan
Apr 1, 1996·Electroencephalography and Clinical Neurophysiology·G I BoormanU R Windhorst
Aug 1, 1996·Electroencephalography and Clinical Neurophysiology·B CalancieJ G Broton
Aug 1, 1958·Journal of Neurology, Neurosurgery, and Psychiatry·R C SCHNEIDERJ BEBIN

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Citations

Feb 4, 2011·Journal of Neuroengineering and Rehabilitation·Angel Gil-AgudoAntonio del Ama-Espinosa
Jul 29, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Qilin CaoScott R Whittemore
Feb 26, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Qilin CaoScott R Whittemore
Apr 23, 2013·Disability and Rehabilitation·Angel Gil-AgudoJosé L Pons
May 16, 2012·The Journal of Physiology·Martin Oudega, Monica A Perez
Feb 8, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·François D RoyMonica A Gorassini
May 18, 1999·Archives of Physical Medicine and Rehabilitation·J W LittleR M Harris
Sep 8, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Blair CalancieJames G Broton
May 18, 2007·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Yong KimHiromoto Ito
Feb 22, 2012·Experimental Neurology·Roland R Roy, V Reggie Edgerton
Jun 29, 2016·Journal of Neurotrauma·Robert M Grumbles, Christine K Thomas
Apr 19, 2002·Brain : a Journal of Neurology·Blair CalancieJames G Broton
Jan 3, 2006·Journal of Neurologic Physical Therapy : JNPT·Maria J Amador, James D Guest
Apr 30, 2021·Frontiers in Neuroscience·V Reggie EdgertonParag N Gad
Jul 1, 2021·Journal of Neuroengineering and Rehabilitation·Gustavo BalbinotJose Zariffa

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