Central Dentinogenic Ghost Cell Tumor: An Update on a Rare Aggressive Odontogenic Tumor

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Amos BuchnerMarilena Vered

Abstract

Dentinogenic ghost cell tumor (DGCT) is a very rare odontogenic lesion, with most knowledge based on single case reports. Therefore, a comprehensive analysis was performed of the clinical and radiologic features of reported cases of DGCT with an emphasis on treatment modalities. This is a case series of DGCTs collected from the literature after a systematic search of Medline's PubMed and Google Scholar. Three additional cases were included from the authors' files. Demographic data of the patients, lesion site and size, and radiologic features were analyzed. Treatment approach and events of recurrence were recorded. Forty-five cases (42 from the literature) were included. The mean age of patients was 39.7 ± 19.3 years (range, 12 to 79 yr) and the male-to-female ratio was 1.8:1. The mandible-to-maxilla ratio was 1.14:1, with the posterior region of the jaws being the most commonly involved site. Radiographically, 78% lesions were unilocular, 67% were mixed radiolucent and radiopaque, and 68% had well-defined borders. The mean lesion size was 4.0 cm (range, 1.8 to 13.0 cm). The primary treatment for 21 patients was conservative surgery consisting of enucleation or curettage. Follow-up information for longer than 1 year (mean, 6.2 ...Continue Reading

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Citations

May 9, 2018·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·José Alcides Almeida de ArrudaRicardo Alves Mesquita
Jul 30, 2019·Journal of Computer Assisted Tomography·Ahmed Abdel Khalek Abdel Razek
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Nov 24, 2020·Case Reports in Dentistry·Radhika Manoj BavleReshma Venugopal
Feb 16, 2021·Oral and Maxillofacial Surgery·Caio César da Silva BarrosÉricka Janine Dantas da Silveira
Mar 28, 2021·International Journal of Surgery Case Reports·Inês SalgadoPedro Gomes
May 1, 2021·Animals : an Open Access Journal From MDPI·Annas SallehMohd Zamri-Saad
Jun 16, 2021·Head and Neck Pathology·Gustavo de Souza VieiraDanielle Castex Conde

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