Central dogma of molecular biology
No abstract listed.
A hypothesis: reciprocal information transfer between oligoribonucleotides and oligopeptides in prebiotic molecular evolution
IRMPD action spectroscopy of alkali metal cation-cytosine complexes: effects of alkali metal cation size on gas phase conformation
Were the first organisms heat engines? A new model for biogenesis and the early evolution of biological energy conversion
Mental symbols and genetic symbols: Analogies between theoretical perspectives in biology and cognitive science
Biocultural orchestration of developmental plasticity across levels: the interplay of biology and culture in shaping the mind and behavior across the life span
A prolegomenon for a viable evolutionary psychology--the myth and the reality: comment on Lickliter and Honeycutt (2003)
Two-dimensional network stability of nucleobases and amino acids on graphite under ambient conditions: adenine, L-serine and L-tyrosine
Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
tRNASer(CGA) differentially regulates expression of wild-type and codon-modified papillomavirus L1 genes
Local combinational variables: an approach used in DNA-binding helix-turn-helix motif prediction with sequence information
Evolutionary forces shaping the Golgi glycosylation machinery: why cell surface glycans are universal to living cells
Information transfer in multienzyme complexes--1. Thermodynamics of conformational constraints and memory effects in the bienzyme glyceraldehyde-3-phosphate-dehydrogenase-phosphoribulokinase complex of Chlamydomonas reinhardtii chloroplasts
Widespread uncoupling between transcriptome and translatome variations after a stimulus in mammalian cells
Post-translational generation of constitutively active cores from larger phosphatases in the malaria parasite, Plasmodium falciparum: implications for proteomics
On the origin of the translation system and the genetic code in the RNA world by means of natural selection, exaptation, and subfunctionalization
Identifying novel helix-loop-helix genes in Caenorhabditis elegans through a classroom demonstration of functional genomics
A software tool to model genetic regulatory networks. Applications to the modeling of threshold phenomena and of spatial patterning in Drosophila
Impaired pre-mRNA processing and altered architecture of 3' untranslated regions contribute to the development of human disorders
A multi-omic analysis of an Enterococcus faecium mutant reveals specific genetic mutations and dramatic changes in mRNA and protein expression
Determining the DNA stability parameters for the breathing dynamics of heterogeneous DNA by stochastic optimization
The regulation of gene expression in eukaryotes: bistability and oscillations in repressilator models
The birth and development of the DNA theory of inheritance: sixty years since the discovery of the structure of DNA
Discovery of cell-type specific regulatory elements in the human genome using differential chromatin modification analysis
Gas Phase Structure of Metal Mediated (Cytosine)2Ag(+) Mimics the Hemiprotonated (Cytosine)2H(+) Dimer in i-Motif Folding
Molecular mechanisms of adaptation emerging from the physics and evolution of nucleic acids and proteins
A coarse-grained model with implicit salt for RNAs: predicting 3D structure, stability and salt effect
DNA-RNA hybrid duplexes with decreasing pyrimidine content in the DNA strand provide structural snapshots for the A- to B-form conformational transition of nucleic acids
Simultaneous purification and fractionation of nucleic acids and proteins from complex samples using bidirectional isotachophoresis
Dichotomy in the definition of prescriptive information suggests both prescribed data and prescribed algorithms: biosemiotics applications in genomic systems
Disease Transmission by Misfolded Prion-Protein Isoforms, Prion-Like Amyloids, Functional Amyloids and the Central Dogma
Building arks for tRNA: structure and function of the Arc1p family of non-catalytic tRNA-binding proteins
Predicting 3D Structure, Flexibility, and Stability of RNA Hairpins in Monovalent and Divalent Ion Solutions
How to deduce and teach the logical and unambiguous answer, namely L = ∑C, to "What is Life?" using the principles of communication?
Integration of multi-omics data of a genome-reduced bacterium: Prevalence of post-transcriptional regulation and its correlation with protein abundances
Commentary: Past, present, and future of epigenetics applied to livestock breeding - Hard versus Soft Lamarckian Inheritance Mechanisms
Genome-wide identification and characterization of tissue-specific RNA editing events in D. melanogaster and their potential role in regulating alternative splicing
Analysis of messenger RNA expression by in situ hybridization using RNA probes synthesized via in vitro transcription
Critical role of bioinformatics in translating huge amounts of next-generation sequencing data into personalized medicine
E Pluribus Unum: 50 Years of Research, Millions of Viruses, and One Goal--Tailored Acceleration of AAV Evolution
Profiling of gene-dependent translational progress in cell-free protein synthesis by real-space imaging
From static to dynamic: the need for structural ensembles and a predictive model of RNA folding and function
Nucleotide distribution and the recognition of coding regions in DNA sequences: an information theory approach
A Novel Method to Predict Highly Expressed Genes Based on Radius Clustering and Relative Synonymous Codon Usage
RNA modification enzymes encoded by the gid operon: Implications in biology and virulence of bacteria
A simple, high-yield synthesis of DNA duplexes containing a covalent, thermally cleavable interstrand cross-link at a defined location
Extracellular and circulating redox- and metalloregulated eRNA and eRNP: copper ion-structured RNA cytokines (angiotropin ribokines) and bioaptamer targets imparting RNA chaperone and novel biofunctions to S100-EF-hand and disease-associated proteins
Extracellular functional noncoding nucleic acid bioaptamers and angiotropin RNP ribokines in vascularization and self-tolerance
A transcriptomics-based kinetic model for ethylene biosynthesis in tomato (Solanum lycopersicum) fruit: development, validation and exploration of novel regulatory mechanisms.
RNA aptamers as genetic control devices: the potential of riboswitches as synthetic elements for regulating gene expression
Holes in the Nuclear Membrane as an Illustration of Gaps in the Understanding of the Biology by Biologists
The human stratum corneum as extended, covalently cross-linked biopolymer: mathematics, molecules, and medicine
On the Ag(+)-cytosine interaction: the effect of microhydration probed by IR optical spectroscopy and density functional theory
The effect of N-acetylcysteine and calcium hydroxide on TNF-α and TGF-β1 in lipopolysaccharide-activated macrophages
The Simplest Flowchart Stating the Mechanisms for Organic Xenobiotics-induced Toxicity: Can it Possibly be Accepted as a "Central Dogma" for Toxic Mechanisms?
Evolutionary dynamics of RNA-like replicator systems: A bioinformatic approach to the origin of life
Mathematical modeling deciphers the benefits of alternatively-designed conserved activatory and inhibitory gene circuits
A frequency-based linguistic approach to protein decoding and design: Simple concepts, diverse applications, and the SCS Package
Chondroprotective potential of Phyllanthus amarus Schum. & Thonn. in experimentally induced cartilage degradation in the explants culture model
iPOP goes the world: integrated personalized Omics profiling and the road toward improved health care
The RNA/protein symmetry hypothesis: experimental support for reverse translation of primitive proteins
LncRNA-HOST2 regulates cell biological behaviors in epithelial ovarian cancer through a mechanism involving microRNA let-7b
Prenatal nutrition and the risk of adult obesity: Long-term effects of nutrition on epigenetic mechanisms regulating gene expression
On the origin of DNA genomes: evolution of the division of labor between template and catalyst in model replicator systems
TRaCE+: Ensemble inference of gene regulatory networks from transcriptional expression profiles of gene knock-out experiments
Cognitive neuroepigenetics: the next evolution in our understanding of the molecular mechanisms underlying learning and memory?
Cyclic mismatch binding ligand CMBL4 binds to the 5'-T-3'/5'-GG-3' site by inducing the flipping out of thymine base
An approach for deciphering patient-specific variations with application to breast cancer molecular expression profiles
Direct and precise length measurement of single, stretched DNA fragments by dynamic molecular combing and STED nanoscopy
Versatility of peptide nucleic acids (PNAs): role in chemical biology, drug discovery, and origins of life
Cardiac Troponin and Tropomyosin: Structural and Cellular Perspectives to Unveil the Hypertrophic Cardiomyopathy Phenotype
Viral and Prion Infections of the Central Nervous System: Radiologic-Pathologic Correlation: From the Radiologic Pathology Archives
Neuronal GPCR OCTR-1 regulates innate immunity by controlling protein synthesis in Caenorhabditis elegans
Information Limited Oligonucleotide Amplification Assay for Affinity-Based, Parallel Detection Studies
Lifestyle and precision diabetes medicine: will genomics help optimise the prediction, prevention and treatment of type 2 diabetes through lifestyle therapy?
Co-detection and sequencing of genes and transcripts from the same single cells facilitated by a microfluidics platform
Integrated omic analysis of oropharyngeal carcinomas reveals human papillomavirus (HPV)-dependent regulation of the activator protein 1 (AP-1) pathway.
Assessment of cellular and serum proteome from tongue squamous cell carcinoma patient lacking addictive proclivities for tobacco, betel nut, and alcohol: Case study
TranslatomeDB: a comprehensive database and cloud-based analysis platform for translatome sequencing data
An epigenomic approach to identifying differential overlapping and cis-acting lncRNAs in cisplatin-resistant cancer cells
Features of Knowledge Building in Biology: Understanding Undergraduate Students' Ideas about Molecular Mechanisms
The Design and Transformation of Biofundamentals: A Nonsurvey Introductory Evolutionary and Molecular Biology Course
Using RNA Sequence and Structure for the Prediction of Riboswitch Aptamer: A Comprehensive Review of Available Software and Tools
Catalysis of a 1,3-dipolar reaction by distorted DNA incorporating a heterobimetallic platinum(ii) and copper(ii) complex
Ancient and modern: hints of a core post-transcriptional network driving chemotherapy resistance in ovarian cancer
Biological classification with RNA-seq data: Can alternatively spliced transcript expression enhance machine learning classifiers?
A Survey of Software and Hardware Approaches to Performing Read Alignment in Next Generation Sequencing
Conceptual Demography in Upper Secondary Chemistry and Biology Textbooks' Descriptions of Protein Synthesis: A Matter of Context?
Overview of high throughput sequencing technologies to elucidate molecular pathways in cardiovascular diseases
Physical models can provide superior learning opportunities beyond the benefits of active engagements
Ultra-acceleration of Photochemical Cytosine Deamination by Using a 5'-Phosphate-Substituted Oligodeoxyribonucleotide Probe Containing a 3-Cyanovinylcarbazole Nucleotide at Its 5'-End
Amino acid modifications for conformationally constraining naturally occurring and engineered peptide backbones: Insights from the Protein Data Bank
YeATS - a tool suite for analyzing RNA-seq derived transcriptome identifies a highly transcribed putative extensin in heartwood/sapwood transition zone in black walnut
Bio-On-Magnetic-Beads (BOMB): Open platform for high-throughput nucleic acid extraction and manipulation
PPI-Detect: A support vector machine model for sequence-based prediction of protein-protein interactions
Selecting Near-Native Protein Structures from Predicted Decoy Sets Using Ordered Graphlet Degree Similarity
The Origin of Prebiotic Information System in the Peptide/RNA World: A Simulation Model of the Evolution of Translation and the Genetic Code
High-throughput genotyping of advanced congenic lines by high resolution melting analysis for identification of Bbaa2, a QTL controlling Lyme arthritis
The electric double layer structure modulates poly-dT25 conformation and adsorption kinetics at the cationic lipid bilayer interface
Translation elicits a growth rate-dependent, genome-wide, differential protein production in Bacillus subtilis
Types and Strains: Their Essential Role in Understanding Protein Aggregation in Neurodegenerative Diseases
In silico survey of the central conserved regions in viroids of the Pospiviroidae family for conserved asymmetric loop structures
A comparative study of multi-omics integration tools for cancer driver gene identification and tumour subtyping.
Sequence Determinants of Substrate Ambiguity in a HAD Phosphosugar Phosphatase of Arabidopsis Thaliana
Escherichia coli Extract-Based Cell-Free Expression System as an Alternative for Difficult-to-Obtain Protein Biosynthesis
Faraway, so close. The comparative method and the potential of non-model animals in mitochondrial research.
AB-alternating copolymers via chain-growth polymerization: synthesis, characterization, self-assembly, and functions
Heritable Epigenetic Changes Alter Transgenerational Waveforms Maintained by Cycling Stores of Information.
Non-coding Natural Antisense RNA: Mechanisms of Action in the Regulation of Target Gene Expression and Its Clinical Implications
Investigating cell cycle-dependent gene expression in the context of nuclear architecture at single-allele resolution.
cncRNAdb: a manually curated resource of experimentally supported RNAs with both protein-coding and noncoding function.
Overview of cell-free protein synthesis: historic landmarks, commercial systems, and expanding applications
Combining a Simple Method for DNA/RNA/Protein Co-Purification and Arabidopsis Protoplast Assay to Facilitate Viroid Research
Untangling the Metabolic Reprogramming in Brain Cancer: Discovering Key Molecular Players Using Mass Spectrometry
Combined transcriptomics and proteomics forecast analysis for potential genes regulating the Columbian plumage color in chickens
Cross-editing by a tRNA synthetase allows vertebrates to abundantly express mischargeable tRNA without causing mistranslation
Epigenetic Research in Stem Cell Bioengineering-Anti-Cancer Therapy, Regenerative and Reconstructive Medicine in Human Clinical Trials
Codon Pairs are Phylogenetically Conserved: A comprehensive analysis of codon pairing conservation across the Tree of Life
Using triple-helix-forming Peptide nucleic acids for sequence-selective recognition of double-stranded RNA
Post-Translational Dosage Compensation Buffers Genetic Perturbations to Stoichiometry of Protein Complexes
Differential regulation of germ line apoptosis and germ cell differentiation by CPEB family members in C. elegans
GeNNet: an integrated platform for unifying scientific workflows and graph databases for transcriptome data analysis
A DAAM1 3'-UTR SNP mutation regulates breast cancer metastasis through affecting miR-208a-5p-DAAM1-RhoA axis
Novel Approaches in Ovarian Cancer Research against Heterogeneity, Late Diagnosis, Drug Resistance, and Transcoelomic Metastases
ExtRamp: a novel algorithm for extracting the ramp sequence based on the tRNA adaptation index or relative codon adaptiveness
A New World of Biomarkers and Therapeutics for Female Reproductive System and Breast Cancers: Circular RNAs
Evolution of RNA- and DNA-guided antivirus defense systems in prokaryotes and eukaryotes: common ancestry vs convergence
Beyond quantification: in situ analysis of transcriptome and pre-mRNA alternative splicing at the nanoscale
O-linked β-N-acetylglucosamine modification of proteins is essential for foot process maturation and survival in podocytes
Regulation-Structured Dynamic Metabolic Model Provides a Potential Mechanism for Delayed Enzyme Response in Denitrification Process
A logic-based dynamic modeling approach to explicate the evolution of the central dogma of molecular biology
On a Robust, Sensitive Cell-Free Method for Pseudomonas Sensing and Quantification in Microfluidic Templated Hydrogels
System-level understanding of gene expression and regulation for engineering secondary metabolite production in Streptomyces.
Unraveling Heterogeneity in Transcriptome and Its Regulation Through Single-Cell Multi-Omics Technologies
Phylogenetic and genomic analyses of the ribosomal oxygenases Riox1 (No66) and Riox2 (Mina53) provide new insights into their evolution
The importance of thermodynamics for molecular systems, and the importance of molecular systems for thermodynamics
Alternative Biochemistries for Alien Life: Basic Concepts and Requirements for the Design of a Robust Biocontainment System in Genetic Isolation
In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release
Long noncoding RNA LINC00342 promotes growth of infantile hemangioma by sponging miR-3619-5p from HDGF
A Nutrigenomics Approach Using RNA Sequencing Technology to Study Nutrient-Gene Interactions in Agricultural Animals
Evidence Supporting That RNA Polymerase II Catalyzes De Novo Transcription Using Potato Spindle Tuber Viroid Circular RNA Templates.
A learning based framework for diverse biomolecule relationship prediction in molecular association network.
Alternative polyadenylation drives genome-to-phenome information detours in the AMPKα1 and AMPKα2 knockout mice
Posttranscriptional (Re)programming of Cell Fate: Examples in Stem Cells, Progenitor, and Differentiated Cells
The Microbiome and the Gut-Liver-Brain Axis for Central Nervous System Clinical Pharmacology: Challenges in Specifying and Integrating In Vitro and In Silico Models.
A model of k -mer surprisal to quantify local sequence information content surrounding splice regions
The Network of Replication, Transcription, and Reverse Transcription of a Synthetic Genetic Cassette.
CRISPR-Mediated Engineering across the Central Dogma in Plant Biology for Basic Research and Crop Improvement.
Processing-independent analysis (PIA): a method for quantitation of the total peptide-gene expression.
Bacterial Vivisection: How Fluorescence-Based Imaging Techniques Shed a Light on the Inner Workings of Bacteria
The vaccinologist's "dirty little secret": a better understanding of structure-function relationships of viral immunogens might advance rational HIV vaccine design.
Small RNA research and the scientific repertoire: a tale about biochemistry and genetics, crops and worms, development and disease.
Bis(phenylethynyl)arene Linkers in Tetracationic Bis-triarylborane Chromophores Control Fluorimetric and Raman Sensing of Various DNAs and RNAs.
Handhold-Mediated Strand Displacement: A Nucleic Acid Based Mechanism for Generating Far-from-Equilibrium Assemblies through Templated Reactions.
A strategy for programming the regulation of in vitro transcription with application in molecular circuits.
Insights on recent approaches in drug discovery strategies and untapped drug targets against drug resistance.
Effects of a Potential Host Gut-Derived Probiotic, Bacillus subtilis 6-3-1, on the Growth, Non-specific Immune Response and Disease Resistance of Hybrid Grouper (Epinephelus fuscoguttatus♀ × Epinephelus lanceolatus♂).
Model of gene transcription including the return of a RNA polymerase to the beginning of a transcriptional cycle
Genotype to Phenotype: CRISPR Gene Editing Reveals Genetic Compensation as a Mechanism for Phenotypic Disjunction of Morphants and Mutants.
Metabolomics bridging proteomics along metabolites/oncometabolites and protein modifications: Paving the way toward integrative multiomics.
Chloroplast acquisition without the gene transfer in kleptoplastic sea slugs, Plakobranchus ocellatus.
Combining genetic algorithm with machine learning strategies for designing potent antimicrobial peptides.
LncRNAs associated with glioblastoma: From transcriptional noise to novel regulators with a promising role in therapeutics.
The Emerging Role of microRNA in Periodontitis: Pathophysiology, Clinical Potential and Future Molecular Perspectives.
The Physics-Biology continuum challenges darwinism: Evolution is directed by the homeostasis-dependent bidirectional relation between genome and phenotype.
Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.
STING Receptor Agonists
Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.
Chronic Fatigue Syndrome
Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.
Hereditary Sensory Autonomic Neuropathy
Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.
Spatio-Temporal Regulation of DNA Repair
DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.
Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.
Separation anxiety is a type of anxiety disorder that involves excessive distress and anxiety with separation. This may include separation from places or people to which they have a strong emotional connection with. It often affects children more than adults. Here is the latest research on separation anxiety.
KIF1A Associated Neurological Disorder
KIF1A associated neurological disorder (KAND) is a rare neurodegenerative condition caused by mutations in the KIF1A gene. KAND may present with a wide range and severity of symptoms including stiff or weak leg muscles, low muscle tone, a lack of muscle coordination and balance, and intellectual disability. Find the latest research on KAND here.
Regulation of Vocal-Motor Plasticity
Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.