PMID: 7034443Apr 1, 1981Paper

Central haemodynamics and oxygen transport with and without continuous positive pressure ventilation after open-heart surgery

Acta Anaesthesiologica Scandinavica
A Vuori

Abstract

Twelve patients, subjected 20 h earlier to coronary artery bypass surgery, were studied on discontinuation of the postoperative mechanical ventilation employing PEEP+5 cmH2O (CMV+PEEP). Compared to the values obtained during CMV+PEEP, cardiac index and mixed venous blood oxygen tension increased with change to spontaneous ventilation at ambient pressure, employing a 28% O2 Ventimask for the intubated patient. There was a slight decrease in both the arterial oxygen content and oxygen tension, but the increase in cardiac output compensated well for the lowering in the arterial oxygen content, and consequently the systemic oxygen transport was statistically unaltered. Oxygen consumption, pulmonary shunt fraction and arteriovenous oxygen content difference also remained unaltered. The observations suggest that after open-heart surgery, CMV using a PEEP as low as +5 cmH2O may exert, in comparison to controlled oxygen therapy ;during spontaneous breathing, a significant lowering effect on the already compromised cardiac performance. This necessitates continuous weighing of the beneficial effects obtained by employing postoperative CMV+PEEP, against the adverse haemodynamic effects, although the alterations in cardiac output may partl...Continue Reading

References

Feb 6, 1975·The New England Journal of Medicine·P M SuterM D Isenberg
Jan 1, 1977·Anesthesia and Analgesia·J B DownsM R Hodges
Jan 1, 1973·The Journal of Thoracic and Cardiovascular Surgery·D G Ashbaugh, T L Petty
Apr 1, 1967·Journal of Applied Physiology·D T Zborowska-Sluis, J B Dossetor
Jul 1, 1967·The American Journal of Physiology·M L NgH A Zieske
Jan 1, 1963·The Journal of Thoracic and Cardiovascular Surgery·J F DAMMANNW H MULLER
Nov 1, 1964·British Journal of Anaesthesia·W R MACRAE, A H MASSON
Jan 1, 1948·The American Journal of Physiology·A COURNAND, H L MOTLEY

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.