PMID: 11320904Apr 26, 2001Paper

Central nervous system involvement in pyothorax-associated lymphoma: ring enhancement on CT scan

Annals of Hematology
S HaraY Mutou

Abstract

A 71-year-old male was diagnosed as having pyothorax-associated lymphoma (PAL), a rare hematological malignancy associated with artificial pneumothorax for the treatment of pulmonary tuberculosis. Because of the low incidence, its clinical features have not been fully clarified. The PAL lesion in this patient disappeared after local radiotherapy and corticosteroid treatment. However, 8 months after the initial diagnosis, he developed a variety of neurological disorders and low-grade fever. Neither recurrence of the primary pulmonary lesion nor nodal enlargement was observed. Immediate magnetic resonance imaging of the brain revealed a ring-enhanced mass, suggesting a brain abscess. However, through a stereotactic biopsy of the brain lesion, infiltration of PAL cells was identified. The brain lesion rapidly enlarged despite intensive radiotherapy, and he finally died of lymphoma progression. This case demonstrates that PAL may progress as a type of extranodal lymphoma, and that brain lesions may produce a ring-enhanced pattern on computed tomography.

Citations

Apr 18, 2009·Japanese Journal of Radiology·Eriko MaedaKuni Ohtomo
Jun 24, 2004·Journal of the American Geriatrics Society·Yann MartinAnne Bornand-Rousselot
Oct 18, 2006·Annals of Oncology : Official Journal of the European Society for Medical Oncology·H NarimatsuS Nakamura

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Abscess

Brain abscess is an accumulation of pus caused by inflammation and infected materials in the brain. Symptoms include fever, headache, seizures and other neurological problems. Discover the latest research on brain abscess today.

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.