Central Neuropathic Pain in Spinal Cord Injury

Critical Reviews in Physical and Rehabilitation Medicine
Sujin LeeEric Chang

Abstract

Spinal cord injury (SCI) is a devastating medical condition affecting 1.2 million people in the United States. Central neuropathic pain is one of the most common medical complications of SCI. Current treatment options include opioids, antiepileptic agents such as gabapentin, antispastic agents such as baclofen or tizanidine, and tricyclic acid. Other options include complementary, nonpharmacological treatment such as exercise or acupuncture, interventional treatments, and psychological approaches. Although these treatment options exist, central neuropathic pain in patients with SCI is still extremely difficult to treat because of its complexity. To develop and provide more effective treatment options to these patients, proper assessment of and classification tools for central neuropathic pain, as well as a better understanding of the pathophysiology, are needed. A combination of approaches, from standard general pain assessments to medically specific questions unique to SCI pathophysiology, is essential for this population. A multidisciplinary approach to patient care, in addition with a better understanding of pathophysiology and diagnosis, will lead to improved management and treatment of patients with SCI displaying central ...Continue Reading

Citations

Dec 24, 2018·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Michihiro OsumiMasahiko Sumitani
Apr 17, 2019·Acta neurologica Belgica·Jaskirat KaurJitendra Kumar Sinha
Aug 6, 2016·Journal of Neurotrauma·Dominic T SchombergDhanansayan Shanmuganayagam
Jan 7, 2021·Neurospine·Nikolay PeevMehmet Zileli
May 1, 2021·International Journal of Molecular Sciences·Hye-Lan LeeKeung-Nyun Kim
Oct 30, 2021·Clinical EEG and Neuroscience·Muhammad A HasanAleksandra Vuckovic
Nov 17, 2021·Neural Regeneration Research·Jiaying ZhengLong-Jun Wu

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