PMID: 9536840Apr 16, 1998Paper

Central-peripheral temperature difference, blood pressure, and arginine vasopressin in preterm neonates undergoing volume expansion

Archives of Disease in Childhood. Fetal and Neonatal Edition
H J LambertM G Coulthard

Abstract

To examine the effect of intravascular volume expansion for the treatment of hypovolaemia in sick preterm neonates. An intravenous infusion of 20 ml per kg of 4.5% albumin was given to 14 preterm neonates. The effects on systolic blood pressure, central peripheral temperature difference (c-pT), and plasma arginine vasopressin concentration (pAVP) were measured. Thirteen babies showed a rise in systolic blood pressure. The six babies with the highest initial values of pAVP and c-pT showed a fall in both of these after infusion. The babies with lower initial pAVP (below 4 pmol/l) showed either a rise (two) or no change (six) after albumin infusion. There was a significant correlation between c-pT and log pAVP before (r2 = 0.61; p < 0.05) and after infusion (r2 = 0.45; p < 0.05). Plasma AVP concentration is related to c-pT in unwell preterm newborns. This study suggests that clinical assessment of hypovolaemia in preterm newborns is poor and could be improved by using c-pT.

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Citations

Mar 9, 2000·Critical Care Medicine·T MatsukawaT Kumazawa
Jun 20, 2002·Critical Care Medicine·Joseph A CarcilloUNKNOWN American College of Critical Care Medicine Task Force Committee Members
Jun 24, 2004·Archives of Disease in Childhood. Fetal and Neonatal Edition·N AladangadyC A J Wardrop
Aug 17, 1999·Archives of Disease in Childhood. Fetal and Neonatal Edition·M G Coulthard, E N Hey
Mar 12, 2010·Early Human Development·Michael Weindling, Fauzia Paize
Jan 30, 2010·Heart & Lung : the Journal of Critical Care·Bernadette M ScheyTracey Bucknall
Jul 16, 2008·Intensive & Critical Care Nursing : the Official Journal of the British Association of Critical Care Nurses·Bernadette M ScheyTracey Bucknall
Jul 10, 2003·Critical Care Clinics·Joseph A Carcillo
Apr 24, 2004·The Cochrane Database of Systematic Reviews·D A Osborn, N Evans

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