Central pontine myelinolysis central pontine myelinolysis manifesting with massive myoclonus

Pediatric Neurology
Hüseyin Tan, Omer Onbaş

Abstract

Central pontine myelinolysis is a rare neurologic disorder defined by symmetric demyelination in the central base of the pons. It usually manifests with neurologic signs such as impaired consciousness, ataxia, spastic quadriparesis, pseudobulbar signs, and the locked-in syndrome which is related to a disconnection syndrome at the pontine level. We report a 17-month-old patient with kwashiorkor and hyponatremia who developed acute massive myoclonus. Magnetic resonance imaging revealed a central pontine lesion. Central pontine myelinolysis is rare in infants, with only a few cases reported in the literature so far. This report presents the first infantile case of central pontine myelinolysis manifesting with massive myoclonus.

References

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Citations

Nov 7, 2009·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Michael L Moritz, Juan Carlos Ayus
Mar 1, 1976·New York State Journal of Medicine·P M IannaconeC C Cornwall
May 11, 2010·Pediatric Emergency Care·Simon EscodaGérard Cheron
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Jun 1, 2012·Journal of Child Neurology·Adrianna M RangerDouglas Fraser
Mar 12, 2010·Metabolic Brain Disease·Michael L Moritz, Juan Carlos Ayus

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