Central serous chorioretinopathy with and without steroids: A multicenter survey

PloS One
Takashi ArakiFumi Gomi

Abstract

We investigated the rates of the use of steroids in Japanese central serous chorioretinopathy (CSC) cases and differences in the characteristics of CSC with and without steroids. A total of 538 eyes of 477 patients diagnosed with CSC, with 3 months or more of follow-up between April 2013 and June 2017 at 8 institutions. Patients with CSC with more than 3 months of follow-up were identified by OCT and fluorescein angiography at 8 institutions. Data collected included patient demographics, history of corticosteroid medication and smoking, spherical errors, findings of angiography, subfoveal choroidal thickness, and changes through the follow-up period. Differences in these findings were analyzed in cases with and without corticosteroid treatment. Among the 477 patients (344 men,133 women), 74 (15.5%) (39 men, 35 women) underwent current or prior steroid treatment. Cases with steroids were higher age (p = 0.0403) and showed no male prevalence, more bilateral involvement (p < 0.0001), and the affected eyes had multiple pigment epithelial detachment (p <0.0001), more fluorescein leakage sites (p < 0.0001), greater choroidal thickness (p = 0.0287) and a higher recurrence rate (p = 0.0412). Steroids can cause severer CSC through an ef...Continue Reading

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Citations

Mar 4, 2020·European Journal of Ophthalmology·Argyrios ChronopoulosLars-Olof Hattenbach
Sep 13, 2020·Scientific Reports·Keigo TakeshimaNorihiro Tsuchiya
Nov 20, 2020·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·Ulrich KellnerGhazaleh Farmand
Feb 4, 2021·Japanese Journal of Ophthalmology·Hisashi FukuyamaFumi Gomi
Feb 7, 2021·Journal of Clinical Medicine·Takeshi KimuraFumi Gomi
May 25, 2021·Progress in Retinal and Eye Research·Richard F SpaidePeter M Maloca
Aug 14, 2021·Japanese Journal of Ophthalmology·Chika TanakaFumi Gomi
Feb 1, 2020·Archivos de la Sociedad Española de Oftalmología·V M Asensio-SánchezJ Valentín-Bravo
Sep 22, 2021·The Journal of Clinical Endocrinology and Metabolism·Joost BrinksOnno C Meijer

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