PMID: 9172046May 1, 1997Paper

Central venous catheter-related septicaemia in paediatric cancer patients

The Journal of Hospital Infection
I DasR H George

Abstract

A prospective study of septicaemia, with special reference to central venous catheter (CVC)-related septicaemia, was performed over a nine-month period in paediatric cancer patients undergoing anti-neoplastic therapy. A total of 142 patients with 153 CVCs were included in the study. Seventy-two episodes of septicaemia were detected in 66 patients; overall, 46% of patients developed one or more episodes of septicaemia. Thirty-nine (54%) of these episodes occurring in 34 patients were CVC-related. Twenty-one (29%) of the episodes occurring in twenty patients were probably unrelated to CVCs and 12 (17%) episodes in 12 patients were of uncertain source. A total of 22932 CVC days were studied. The rate of CVC-related septicaemia was 1.7 episodes/1000 catheter days. Gram-positive organisms were commonest, causing 34 (87%) episodes of CVC-related septicaemia. Twenty-five (71%) of 35 evaluable episodes were successfully treated with antibiotics without CVC removal. Two patients died, CVC related sepsis probably contributing to death, and one patient suffered prolonged morbidity associated with CVC sepsis. Gram-negative organisms were the commonest cause of CVC-unrelated septicaemia, being implicated in 13 (62%) episodes.

References

Jun 9, 1977·The New England Journal of Medicine·D G MakiH W Sarafin

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Citations

Aug 26, 1999·Seminars in Oncology Nursing·B K Shelton
Nov 27, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R HauptE Castagnola
Aug 9, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Aditya H GaurRandall T Hayden
Sep 6, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Deborah TomlinsonLillian Sung
Jun 10, 2015·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Hirozumi SanoKunihiko Kobayashi
Oct 4, 2008·Best Practice & Research. Clinical Anaesthesiology·Walter ZinggBernhard Walder
Sep 1, 2005·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·S C PaulusB L Pizer
Dec 21, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M R MillarE M Hennessy
Mar 11, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Simone CesaroModesto Carli
Feb 16, 1999·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·J RobbinsD N Korones
Jan 29, 2005·Annals of Oncology : Official Journal of the European Society for Medical Oncology·G FratinoR Haupt
Jan 10, 2009·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Geraldo SadoyamaPaulo Pinto Gontijo Filho
Apr 29, 2009·Acta Paediatrica·Sólveig HafsteinsdóttirAsgeir Haraldsson
Nov 24, 1999·Current Opinion in Clinical Nutrition and Metabolic Care·F C Albuquerque Júnior, P R Vasconcelos
Feb 16, 1999·Seminars in Surgical Oncology·P W Dillon

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