Cephalosporin antibiotics in the aquatic environment: A critical review of occurrence, fate, ecotoxicity and removal technologies

Environmental Pollution
Alyson R RibeiroTorsten C Schmidt

Abstract

Due to their widespread occurrence in the aquatic environment, human and veterinary cephalosporin antibiotics have been studied as water pollutants. In order to characterize environmental risks of this compound class, this review evaluates relevant data about physicochemical properties, occurrence, ecotoxicity and degradation of cephalosporins. Although application of cephalosporins is rather low compared to other antibiotics and their environmental life-time is believed to be short (i.e. days), the available data is insufficient to draw conclusions on their environmental relevance. Few studies concerning the fate of cephalosporins in soil are available, while hydrolysis and photo-degradation are suggested as the main attenuation processes in the aquatic environment. Cephalosporins have been detected in different aqueous matrices in concentrations ranging from 0.30 ng L-1 to 0.03 mg L-1, with sewage and wastewater being the main matrices with positive findings. For wastewater treatment purposes, several technologies have been tested for the abatement of cephalosporins, including photolysis and adsorption. In most cases, the technology employed led to complete or significant removal (>95%) of parental drugs but few authors repor...Continue Reading

Citations

Mar 2, 2019·Environmental Science. Processes & Impacts·Ming-Hao HsuAngela Yu-Chen Lin
Aug 15, 2020·Journal of Medical Systems·Marc KostrubiakMitchell H Tsai
Nov 22, 2019·European Journal of Pharmacology·Ewa FelisEwa Korzeniewska
Nov 10, 2020·Biosensors & Bioelectronics·Patrícia RebeloCristina Delerue-Matos
May 1, 2021·International Journal of Environmental Research and Public Health·Gerardo LeónBeatriz Miguel
Jan 27, 2019·Environment International·Mohit KumarPratyoosh Shukla
Apr 30, 2021·MSphere·Christopher FröhlichHanna-Kirsti S Leiros
Jun 6, 2021·Environmental Science and Pollution Research International·Shijie YaoChangzheng Cui
Dec 12, 2019·Analytical Chemistry·Susan D Richardson, Susana Y Kimura
May 22, 2020·Ecotoxicology and Environmental Safety·Zhen LiXiang Liu
Dec 17, 2021·The Science of the Total Environment·Mingyeong KangWoojun Park

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