Cerclages after Femoral Osteotomy Are at Risk for Bacterial Colonization during Two-Stage Septic Total Hip Arthroplasty Revision

Journal of Bone and Joint Infection
Viktor JanzMichael Müller

Abstract

Aims: In cases of a two-stage septic total hip arthroplasty (THA) exchange a femoral osteotomy with subsequent cerclage stabilization may be necessary to remove a well-fixed stem. This study aims to investigate the rate of bacterial colonization and risk of infection persistence associated with in situ cerclage hardware in two-stage septic THA exchange. Patients and Methods: Twenty-three patients undergoing two-stage THA exchange between 2011 and 2016 were included in this retrospective cohort study. During the re-implantation procedure synovial fluid, periprosthetic tissue samples and sonicate fluid cultures (SFC) of the cerclage hardware were acquired. Results: Seven of 23 (30%) cerclage-SFC produced a positive bacterial isolation. Six of the seven positive cerclage-SFC were acquired during THA re-implantation. Two of the seven patients (29%) with a positive bacterial isolation from the cerclage hardware underwent a THA-revision for septic complications. The other five patients had their THA in situ at last follow-up. Conclusions: Despite surgical debridement and antimicrobial therapy, a bacterial colonization of cerclage hardware occurs and poses a risk for infection persistence. All cerclage hardware should be removed or ex...Continue Reading

References

Nov 25, 1998·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E F BerbariD R Osmon
Oct 16, 2004·The New England Journal of Medicine·Werner ZimmerliPeter E Ochsner
Mar 17, 2006·Nature Reviews. Microbiology·Richard A ProctorGeorg Peters
Dec 14, 2006·Archives of Orthopaedic and Trauma Surgery·Alexander C DischCarsten Perka
Mar 9, 2007·Operative Orthopädie und Traumatologie·Bernd Fink, Alexandra Grossmann
Apr 4, 2008·Clinical Orthopaedics and Related Research·Renuka Reddy KuruvalliTudor Lloyd Thomas
Oct 22, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Peter SchäferLars Frommelt
Aug 9, 2011·Clinical Orthopaedics and Related Research·Daniel F A de MenezesMathias Goldschild
Dec 20, 2011·The Journal of Arthroplasty·Daniel R P NeumannUlrich Dorn
Apr 3, 2012·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Enrique Gómez-BarrenaJosé A Puértolas
Oct 16, 2012·The International Journal of Artificial Organs·Johannes HolinkaElisabeth Presterl
Dec 12, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Douglas R OsmonUNKNOWN Infectious Diseases Society of America
Mar 25, 2014·Clinical Orthopaedics and Related Research·Charles L NelsonThomas R Bowen
Apr 4, 2014·Clinical Microbiology Reviews·Aaron J Tande, Robin Patel
Mar 6, 2015·Journal of Clinical Microbiology·María Eugenia PortilloLluis Puig-Verdie
Nov 28, 2015·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J EstebanJ Cordero-Ampuero
Jan 5, 2016·The Journal of Arthroplasty·Bernd Fink, Damian Oremek

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Mar 17, 2020·EFORT Open Reviews·Konrad Sebastian WronkaPeter Herman Johan Cnudde

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