Cereal products derived from wheat, sorghum, rice and oats alter the infant gut microbiota in vitro

Scientific Reports
Hasinika K A H GamageIan T Paulsen

Abstract

The introduction of different nutrient and energy sources during weaning leads to significant changes in the infant gut microbiota. We used an in vitro infant digestive and gut microbiota model system to investigate the effect of four commercially available cereal products based on either wheat, sorghum, rice or oats, on the gut microbiota of six infants. Our results indicated cereal additions induced numerous changes in the gut microbiota composition. The relative abundance of bacterial families associated with fibre degradation, Bacteroidaceae, Bifidobacteriaceae, Lactobacillaceae, Prevotellaceae, Ruminococcaceae and Veillonellaceae increased, whilst the abundance of Enterobacteriaceae decreased with cereal additions. Corresponding changes in the production of SCFAs showed higher concentrations of acetate following all cereal additions, whilst, propionate and butyrate varied between specific cereal additions. These cereal-specific variations in the concentrations of SCFAs showed a moderate correlation with the relative abundance of potential SCFA-producing bacterial families. Overall, our results demonstrated clear shifts in the abundance of bacterial groups associated with weaning and an increase in the production of SCFAs f...Continue Reading

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Citations

Mar 1, 2019·Nutrients·Michelle KlerksLuis Manuel Sanchez-Siles
May 18, 2019·Current Gastroenterology Reports·Daniel R DuncanRachel L Rosen
Dec 15, 2018·BMC Microbiology·Hui YangLusheng Huang
Oct 18, 2020·Microorganisms·Shanthi G ParkarKerry L Bentley-Hewitt
Oct 22, 2020·International Journal of Molecular Sciences·Silvia Fernández-PérezLeandro B Rodríguez-Aparicio
Oct 30, 2020·Expert Opinion on Drug Safety·Melina SimonYvan Vandenplas
Jul 7, 2019·Microorganisms·Starin McKeenWarren C McNabb
Mar 29, 2021·The Science of the Total Environment·Najiaowa YuYang Liu
Jul 13, 2021·Biotechnology Advances·Elora FournierStéphanie Blanquet-Diot
Sep 7, 2021·The Journal of Nutrition·Ezra ValidoMarija Glisic

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Methods Mentioned

BETA
Phosphotransferase

Software Mentioned

Greengenes
PICRUSt
GraphPad Prism
PRIMER
GraphPad
QIIME
ANOSIM
Quantitative Insights Into Microbial Ecology ( QIIME )

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